Lewis R B, Castor C W, Knisley R E, Bole G G
Arthritis Rheum. 1976 Nov-Dec;19(6):1256-60. doi: 10.1002/art.1780190605.
A patient population admitted to the hospital for either SLE or RA was surveyed for the subsequent development of neoplasms. The frequency of neoplasm in SLE patients appeared to be exaggerated, whereas the frequency of subsequent neoplasm in rheumatoid patients was unexpectedly low. A paucity of nephritis in the SLE group was noted. Further reports are encouraged so that the magnitude of the risk of malignancy developing with immunosuppressive therapy can be more precisely ascertained.
对因系统性红斑狼疮（SLE）或类风湿性关节炎（RA）入院的患者群体进行了肿瘤后续发展情况的调查。SLE患者的肿瘤发生率似乎被高估了，而类风湿患者后续发生肿瘤的频率却出乎意料地低。注意到SLE组肾炎较少。鼓励进一步报告，以便能更准确地确定免疫抑制治疗导致恶性肿瘤发生风险的程度。
