Ng John, Lee Percy
Department of Radiation Oncology, Weill Cornell Medical College, New York-Presbyterian Hospital, 525 East 68th Street, N-046, New York, NY 10065, USA.
Department of Radiation Oncology, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California Los Angeles, 200 UCLA Medical Plaza, B265, Los Angeles, CA 90095, USA.
Hematol Oncol Clin North Am. 2017 Jun;31(3):453-468. doi: 10.1016/j.hoc.2017.01.005. Epub 2017 Mar 22.
Multimodality management has become a core treatment principle for locally advanced esophageal, gastroesophageal junction (GEJ), and gastric cancer. Radiotherapy serves an important role for optimizing patient outcomes. This article reviews the evolving role of radiotherapy in the multidisciplinary management of esophageal, GEJ, and gastric cancer, summarizing the results of recent clinical trials leading to contemporary accepted treatment approaches. A major theme is the evidence supporting the role of radiotherapy in combined modality management, particularly the trend toward its delivery in the neoadjuvant setting. Also reviewed are novel radiotherapy paradigms and newer radiation technologies such as image-guided radiotherapy and MRI-guided radiotherapy.
多模态管理已成为局部晚期食管癌、胃食管交界部（GEJ）癌和胃癌的核心治疗原则。放射治疗在优化患者治疗效果方面发挥着重要作用。本文回顾了放射治疗在食管癌、GEJ癌和胃癌多学科管理中不断演变的作用，总结了近期临床试验的结果，这些结果促成了当代公认的治疗方法。一个主要主题是支持放射治疗在联合治疗模式中作用的证据，特别是在新辅助治疗环境中进行放射治疗的趋势。还回顾了新型放射治疗模式和更新的放射技术，如图像引导放射治疗和磁共振成像引导放射治疗。
