小儿炎症性肠病

Pediatric Inflammatory Bowel Disease.

作者信息

Conrad Máire A, Rosh Joel R

机构信息

Division of Gastroenterology, Hepatology and Nutrition, The Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, 3401 Civic Center Boulevard, Philadelphia, PA 19104, USA.

Pediatric Gastroenterology, Clinical Development and Research Affairs, Goryeb Children's Hospital/Atlantic Health, Icahn School of Medicine at Mount Sinai, 100 Madison Avenue, Morristown, NJ 07962, USA.

出版信息

Pediatr Clin North Am. 2017 Jun;64(3):577-591. doi: 10.1016/j.pcl.2017.01.005.

DOI:10.1016/j.pcl.2017.01.005

PMID:28502439

Abstract

Inflammatory bowel disease (IBD), including Crohn disease, ulcerative colitis, and IBD-unspecified, is a chronic immune-mediated condition of the gastrointestinal tract in which the goal of treatment is to induce and maintain durable remission. In pediatrics, there is a wide spectrum of presenting symptoms, but esophagogastroduodenoscopy and colonoscopy are imperative to confirming the diagnosis. Treatment goals include achieving mucosal healing of the gastrointestinal tract, reaching growth potential, limiting medication toxicities, and optimizing quality of life for all patients.

摘要

炎症性肠病（IBD），包括克罗恩病、溃疡性结肠炎和未分类的IBD，是一种慢性免疫介导的胃肠道疾病，其治疗目标是诱导并维持持久缓解。在儿科中，呈现的症状范围广泛，但食管胃十二指肠镜检查和结肠镜检查对于确诊至关重要。治疗目标包括实现胃肠道黏膜愈合、达到生长潜能、限制药物毒性以及优化所有患者的生活质量。