胰腺疾病
Pancreatic Disorders.
作者信息
Uc Aliye, Fishman Douglas S
机构信息
Division of Pediatric Gastroenterology, Stead Family Department of Pediatrics, University of Iowa Carver College of Medicine, BT 1120-C, 200 Hawkins Drive, Iowa City, IA 52242, USA.
Section of Pediatric Gastroenterology, Hepatology, and Nutrition, Texas Children's Hospital, Baylor College of Medicine, 6701 Fannin Street, Clinical Care Tower, 1010, Houston, TX 77030, USA.
出版信息
Pediatr Clin North Am. 2017 Jun;64(3):685-706. doi: 10.1016/j.pcl.2017.01.010.
Once considered uncommon, pancreatic diseases are increasingly recognized in the pediatric age group. Acute pancreatitis, acute recurrent pancreatitis, and chronic pancreatitis occur in children with an incidence approaching that of adults. Risk factors are broad, prompting the need for a completely different diagnostic and therapeutic approach in children. Although cystic fibrosis remains the most common cause of exocrine pancreatic insufficiency, other causes such as chronic pancreatitis may be as common as Shwachman Diamond syndrome. Long-term effects of pancreatic diseases may be staggering, as children suffer from significant disease burden, high economic cost, nutritional deficiencies, pancreatogenic diabetes, and potentially pancreatic cancer.
胰腺疾病曾经被认为不常见，但现在在儿童年龄组中越来越受到关注。急性胰腺炎、急性复发性胰腺炎和慢性胰腺炎在儿童中的发病率接近成人。危险因素广泛，这促使在儿童中需要一种完全不同的诊断和治疗方法。虽然囊性纤维化仍然是外分泌性胰腺功能不全最常见的原因，但其他原因如慢性胰腺炎可能与施瓦茨曼-戴蒙德综合征一样常见。胰腺疾病的长期影响可能令人震惊，因为儿童承受着巨大的疾病负担、高昂的经济成本、营养缺乏、胰源性糖尿病，甚至可能患胰腺癌。
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