Stippler Martina, Liu Jingyi, Motiei-Langroudi Rouzbeh, Voronovich Zoya, Yonas Howard, Davis Roger B
Neurosurgery Service, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
School of Medicine, Harvard Medical School, Boston, Massachusetts, USA.
World Neurosurg. 2017 Sep;105:265-269. doi: 10.1016/j.wneu.2017.05.008. Epub 2017 May 11.
To evaluate the need for repeat head computed tomography (CT) in patients with complicated mild traumatic brain injury (TBI) determined nonoperative after the first head CT.
A total of 380 patients with mild TBI and a positive head CT not needing surgery were included. Changes between first and second head CT were categorized as decreased, increased, or stable.
Three patients required neurosurgical intervention (0.8%) after the second CT. There were no significant differences in demographics including age, gender, alcohol consumption, anticoagulation status, time between first and second CT, Glasgow Coma Scale score at admission and discharge, and incidence of subarachnoid hemorrhage, epidural hematoma, contusion, or skull fractures between the operated and nonoperated groups. All patients in the operated group had subdural hematoma compared with 40.8% in the nonoperated group (P = 0.07). All operated patients showed symptoms of neurologic worsening after initial head CT, compared with 2.7% in the nonoperated group (P < 0.001). Moreover, patients who showed neurologic worsening were more likely to show increased intracranial bleeding on repeat head CT, whereas patients who did not show neurologic worsening were more likely to show decreased or stable intracranial bleeding (P = 0.04).
Routine repeat head CT in patients with complicated mild TBI is very low yield to predict need for delayed surgical intervention. Instead, serial neurologic examination and observation over the first 8 hours after the injury is recommended. A second CT scan should be obtained only in patients who have neurologic worsening.
评估首次头颅计算机断层扫描(CT)后确定非手术治疗的复杂轻度创伤性脑损伤(TBI)患者重复进行头颅CT检查的必要性。
纳入380例轻度TBI且头颅CT阳性无需手术的患者。首次和第二次头颅CT的变化分为减少、增加或稳定。
第二次CT检查后3例患者需要神经外科干预(0.8%)。手术组和非手术组在人口统计学特征方面无显著差异,包括年龄、性别、饮酒情况、抗凝状态、首次和第二次CT检查之间的时间、入院和出院时的格拉斯哥昏迷量表评分以及蛛网膜下腔出血、硬膜外血肿、挫伤或颅骨骨折的发生率。手术组所有患者均有硬膜下血肿,而非手术组为40.8%(P = 0.07)。所有手术患者在初次头颅CT检查后均出现神经功能恶化症状,而非手术组为2.7%(P < 0.001)。此外,出现神经功能恶化的患者在重复头颅CT检查时更有可能出现颅内出血增加,而未出现神经功能恶化的患者更有可能出现颅内出血减少或稳定(P = 0.04)。
复杂轻度TBI患者常规重复头颅CT检查预测延迟手术干预需求的收益非常低。相反,建议在受伤后的前8小时进行连续神经学检查和观察。仅在出现神经功能恶化的患者中进行第二次CT扫描。