Fábrega-Foster Kelly, Ghasabeh Mounes Aliyari, Pawlik Timothy M, Kamel Ihab R
The Russell H. Morgan Department of Radiology and Radiological Sciences Johns Hopkins University, 600 North Wolfe Street, MRI 143, Baltimore, Maryland, USA.
Department of Surgery, The Urban Meyer III and Shelley Meyer Chair in Cancer Research, The Ohio State University Wexner Medical Center, USA.
Hepatobiliary Surg Nutr. 2017 Apr;6(2):67-78. doi: 10.21037/hbsn.2016.12.10.
Intrahepatic cholangiocarcinomas account for approximately 20% of cases of cholangiocarcinomas. Three growth patterns or morphologic subtypes exist, including mass-forming, periductal-infiltrating, and intraductal-growth subtypes. Knowledge of these morphologic subtypes and their radiologic appearance aids in timely diagnosis, a key to optimizing patient outcomes. The morphologic variability of intrahepatic cholangiocarcinomas has a direct impact on the diagnostic sensitivity and specificity of various diagnostic imaging modalities, including ultrasound (US), computed tomography (CT), magnetic resonance imaging (MRI)/magnetic resonance cholangiopancreatography (MRCP), and positron emission tomography (PET). The following review emphasizes optimal imaging technique for each of these modalities and reviews the imaging appearance of each morphologic subtype of intrahepatic cholangiocarcinoma.
肝内胆管癌约占胆管癌病例的20%。存在三种生长模式或形态学亚型，包括肿块型、胆管周围浸润型和管内生长型。了解这些形态学亚型及其影像学表现有助于及时诊断，这是优化患者治疗结果的关键。肝内胆管癌的形态学变异性直接影响包括超声（US）、计算机断层扫描（CT）、磁共振成像（MRI）/磁共振胰胆管造影（MRCP）和正电子发射断层扫描（PET）在内的各种诊断成像方式的诊断敏感性和特异性。以下综述强调了这些成像方式中的每一种的最佳成像技术，并回顾了肝内胆管癌各形态学亚型的影像学表现。
