Moiseev S V, Kornev B M, Eventov A Z, Pisareva N A, Shatkovskiĭ N P
Kardiologiia. 1988 Jul;28(7):41-4.
Marked clinical or electrocardiographic changes, suggestive of heart disease, were only detected in 14 (7%) of 190 patients with sarcoidosis. Diffuse myocardial accumulation of 99mTc pyrophosphate (2+ or 3+) was seen in 12 (43%) of 28 patients with active sarcoidosis. Repeated scintigraphy showed normal values in 3 patients after a course of corticosteroid therapy. Echocardiographic signs of heart disease were found in 33 (37%) of 89 patients, including left-ventricular contractility disorders in 21, thinning (5) or thickening (7) of left-ventricular wall and ventricular septum, mitral prolapse in 3 and limited pericardial exudate in 5. Signs of pulmonary heart were detected in 17 patients. Clinical and electrocardiographic symptoms of cardiac sarcoidosis were significantly more frequent in patients with myocardial Tc-pyrophosphate accumulation and echocardiographic changes. It is suggested that myocardial Tc-pyrophosphate scintigraphy and echocardiography may be used for the diagnosis of cardiac sarcoidosis, including its latent forms.
在190例结节病患者中，仅有14例（7%）出现提示心脏病的明显临床或心电图改变。28例活动性结节病患者中有12例（43%）出现99mTc焦磷酸盐在心肌弥漫性积聚（2+或3+）。3例患者在接受一个疗程的皮质类固醇治疗后，重复闪烁扫描显示结果正常。89例患者中有33例（37%）发现心脏病的超声心动图征象，其中21例出现左心室收缩功能障碍，5例左心室壁和室间隔变薄，7例增厚，3例二尖瓣脱垂，5例有局限性心包积液。17例患者检测到肺心病征象。心肌Tc-焦磷酸盐积聚和超声心动图改变的患者出现心脏结节病的临床和心电图症状明显更频繁。提示心肌Tc-焦磷酸盐闪烁扫描和超声心动图可用于心脏结节病的诊断，包括其隐匿形式。
