Yazaki Y, Kumazaki S, Yamada H, Sekiguchi M
1st Department of Internal Medicine, Shinshu University School of Medicine.
Nihon Rinsho. 1994 Jun;52(6):1582-9.
To analyze the clinical features of cardiac sarcoidosis, we reviewed case reports and clinical investigations from Japan and other countries. Female patients were more frequently affected in this disease in Japan. Cardiac sarcoidosis is characterized by a high incidence of complete atrioventricular block, right bundle branch block, and ventricular arrhythmias on the electrocardiogram. Echocardiography often reveals left ventricular dilatation with systolic dysfunction and wall thickening or thinning. Radionuclide testings, such as, thallium-201, gallium-67 or technetium-99m pyrophosphate, are useful for detecting cardiac involvement and evaluating efficacy of corticosteroid therapy in patients with sarcoidosis. Most of the patients died due to recurrent or refractory heart failure. It is noteworthy that cases of sudden death during stable cardiac function have become infrequent.
为分析心脏结节病的临床特征，我们回顾了来自日本及其他国家的病例报告和临床研究。在日本，女性患者更易患此病。心脏结节病的心电图特征为完全性房室传导阻滞、右束支传导阻滞及室性心律失常的发生率较高。超声心动图常显示左心室扩张伴收缩功能障碍以及室壁增厚或变薄。放射性核素检查，如铊-201、镓-67或锝-99m焦磷酸盐，对于检测结节病患者的心脏受累情况及评估皮质类固醇治疗的疗效很有用。大多数患者死于反复或难治性心力衰竭。值得注意的是，心功能稳定期间发生猝死的病例已变得罕见。
