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成人注意力缺陷多动障碍认知行为疗法的荟萃分析。

Meta-analysis of cognitive-behavioral treatments for adult ADHD.

作者信息

Knouse Laura E, Teller Jonathan, Brooks Milan A

机构信息

Department of Psychology, University of Richmond.

出版信息

J Consult Clin Psychol. 2017 Jul;85(7):737-750. doi: 10.1037/ccp0000216. Epub 2017 May 15.

Abstract

OBJECTIVE

We conducted a meta-analysis of cognitive-behavioral treatment (CBT) studies for adult attention-deficit/hyperactivity disorder (ADHD), examining effects versus control and effects pre-to-post treatment to maximize the clinical and research utility of findings from this growing literature.

METHOD

Eligible studies tested adults meeting criteria for Diagnostic and Statistical Manual of Mental Disorders ADHD as determined by interview or using a standardized rating scale and measured ADHD symptoms or related impairment at baseline and posttreatment. We analyzed data from 32 studies from published and unpublished sources available through December 2015. Effect size calculations included up to 896 participants.

RESULTS

Using a random effects model, we found that CBTs had medium-to-large effects from pre- to posttreatment (self-reported ADHD symptoms: g = 1.00; 95% confidence interval [CI: 0.84, 1.16]; self-reported functioning g = .73; 95% CI [0.46, 1.00]) and small-to-medium effects versus control (g = .65; 95% CI [0.44, 0.86] for symptoms, .51; 95% CI [0.23, 0.79] for functioning). Effect sizes were heterogeneous for most outcome measures. Studies with active control groups showed smaller effect sizes. Neither participant medication status nor treatment format moderated pre-to-post treatment effects, and longer treatments were not associated with better outcomes.

CONCLUSIONS

Current CBTs for adult ADHD show comparable effect sizes to behavioral treatments for children with ADHD, which are considered well-established treatments. Future treatment development could focus on identifying empirically supported principles of treatment-related change for adults with ADHD. We encourage researchers to report future findings in a way that is amenable to meta-analytic review. (PsycINFO Database Record

摘要

目的

我们对成人注意力缺陷多动障碍(ADHD)的认知行为治疗(CBT)研究进行了一项荟萃分析,比较其与对照组的疗效以及治疗前后的效果,以最大限度地提高这一不断增长的文献中研究结果的临床和研究效用。

方法

符合条件的研究对通过访谈或使用标准化评定量表确定符合《精神疾病诊断与统计手册》ADHD标准的成年人进行了测试,并在基线和治疗后测量了ADHD症状或相关损害。我们分析了截至2015年12月可从已发表和未发表来源获得的32项研究的数据。效应量计算纳入了多达896名参与者。

结果

使用随机效应模型,我们发现CBT治疗前后有中到较大的效应(自我报告的ADHD症状:g = 1.00;95%置信区间[CI:0.84, 1.16];自我报告的功能g = 0.73;95% CI [0.46, 1.00]),与对照组相比有小到中等的效应(症状g = 0.65;95% CI [0.44, 0.86],功能g = 0.51;95% CI [0.23, 0.79])。大多数结局指标的效应量存在异质性。有积极对照组的研究显示效应量较小。参与者的用药状态和治疗形式均未调节治疗前后的效应,且治疗时间较长与更好的结局无关。

结论

目前针对成人ADHD的CBT显示出与针对儿童ADHD的行为治疗相当的效应量,而后者被认为是成熟的治疗方法。未来的治疗发展可以专注于确定针对成人ADHD的与治疗相关变化的经验支持原则。我们鼓励研究人员以适合荟萃分析审查的方式报告未来的研究结果。(PsycINFO数据库记录

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