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超高龄患者入住重症监护病房的成本分析。

Cost analysis of the very elderly admitted to intensive care units.

机构信息

Department of Medicine, University of Ottawa/The Ottawa Hospital, 501 Smyth Rd., Ottawa, Ontario, K1H 8L6, Canada.

Ottawa Hospital Research Institute, The Ottawa Hospital, Ottawa, Ontario, Canada.

出版信息

Crit Care. 2017 May 16;21(1):109. doi: 10.1186/s13054-017-1689-y.

Abstract

BACKGROUND

Very elderly patients are often admitted to intensive care units (ICUs) despite poor outcomes and frequent preference to avoid unnecessary prolongation of life. We sought to determine the cost of ICU admission for the very elderly and the factors influencing this cost.

METHODS

This prospective, observational cohort study included patients ≥80 years old admitted to 22 Canadian ICUs from 2009 to 2013. A subset of consenting individuals comprised a longitudinal cohort followed over 12 months. Costs were calculated from ICU length of stay and unit costs for ICU admission from a Canadian academic hospital. A generalized linear model was employed to identify cost-predictive variables.

RESULTS

In total, 1671 patients were included; 610 were enrolled in the longitudinal cohort. The average age was 85 years; median ICU length of stay was 4 days. Mortality was 35% (585/1671) in hospital and 41% (253/610) at 12 months. The average cost of ICU admission per patient was $31,679 ± 65,867. Estimated ICU costs were $48,744 per survivor to discharge and $61,783 per survivor at 1 year. For both decedents and survivors, preference for comfort measures over life support was an independent predictor for lower cost (P < 0.01).

CONCLUSIONS

Considering the poor clinical outcomes, and that many ICU admissions may be undesired by very elderly patients, ICU costs in this population are substantial. Our finding that a preference for comfort care predicted a lower cost independent of mortality reinforces the importance of early goals of care discussions to avoid both undesired and potentially non-beneficial interventions, consequently reducing costs.

TRIAL REGISTRATION

ClinicalTrials.gov, NCT01293708 . Registered on 10 February 2011.

摘要

背景

尽管预后较差且经常倾向于避免不必要的生命延长,但非常高龄的患者仍经常被收入重症监护病房(ICU)。我们旨在确定 ICU 对非常高龄患者的入院成本,以及影响该成本的因素。

方法

这项前瞻性观察性队列研究纳入了 2009 年至 2013 年期间在加拿大 22 家 ICU 接受治疗的 80 岁及以上患者。其中,一组同意的个体组成了一个纵向队列,随访 12 个月。ICU 住院时间和 ICU 入院单位成本来自一家加拿大学术医院,以此来计算成本。采用广义线性模型确定成本预测变量。

结果

共纳入 1671 例患者,其中 610 例纳入纵向队列。平均年龄为 85 岁,中位 ICU 住院时间为 4 天。院内死亡率为 35%(585/1671),12 个月时死亡率为 41%(253/610)。每位患者 ICU 入院的平均费用为 31679 美元±65867 美元。估计每个幸存者出院的 ICU 费用为 48744 美元,1 年后幸存者的 ICU 费用为 61783 美元。对于死亡者和幸存者,与生命支持相比,更倾向于舒适治疗是降低成本的独立预测因素(P<0.01)。

结论

考虑到较差的临床结局,以及许多 ICU 入院可能是非常高龄患者不希望的,该人群的 ICU 成本很高。我们的研究发现,舒适护理的偏好独立于死亡率预测了较低的成本,这进一步强调了早期进行治疗目标讨论的重要性,以避免不必要的和潜在无益的干预,从而降低成本。

试验注册

ClinicalTrials.gov,NCT01293708。于 2011 年 2 月 10 日注册。

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