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[精神药物治疗期间精神分裂症患者的动态免疫反应性:以病毒诱导的血液淋巴细胞反应为例]

[Dynamic immunologic reactivity of schizophrenics during psychopharmacotherapy as exemplified by virus-induced reactions of the blood lymphocytes].

作者信息

Nevidimova T I, Vasil'eva O A, Krasik E D, Logvinovich G V

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1988;88(10):81-7.

PMID:2850696
Abstract

Clinical immunological investigation of 149 schizophrenic patients, 89 healthy donors and 38 infected patients revealed the fact of high lymphocyte reactivity in schizophrenic patients inhabitants of the city of Tomsk and Tomsk Province to the viral antigens of herpes simplex and Far-Eastern encephalitis. The course of herpes-induced immune responses was largely associated with the course of psychopathological signs. The role of immunomodulating and desensitizing effects of psychotropic therapy is discussed.

摘要

对149名精神分裂症患者、89名健康献血者和38名感染患者进行的临床免疫学调查显示,托木斯克市和托木斯克州的精神分裂症患者对单纯疱疹病毒抗原和远东脑炎病毒抗原的淋巴细胞反应性较高。疱疹诱导的免疫反应过程在很大程度上与精神病理症状的过程相关。文中讨论了精神药物治疗的免疫调节和脱敏作用。

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[Dynamic immunologic reactivity of schizophrenics during psychopharmacotherapy as exemplified by virus-induced reactions of the blood lymphocytes].[精神药物治疗期间精神分裂症患者的动态免疫反应性:以病毒诱导的血液淋巴细胞反应为例]
Zh Nevropatol Psikhiatr Im S S Korsakova. 1988;88(10):81-7.
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