Assembly and function of bHLH-PAS complexes.
作者信息
Fribourgh Jennifer L, Partch Carrie L
机构信息
Department of Chemistry and Biochemistry, University of California, Santa Cruz, CA 96054.
Department of Chemistry and Biochemistry, University of California, Santa Cruz, CA 96054;
出版信息
Proc Natl Acad Sci U S A. 2017 May 23;114(21):5330-5332. doi: 10.1073/pnas.1705408114. Epub 2017 May 15.
Abstract
摘要
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本文引用的文献
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Structural hierarchy controlling dimerization and target DNA recognition in the AHR transcriptional complex.结构层次控制 AHR 转录复合物中二聚化和靶 DNA 识别。
Proc Natl Acad Sci U S A. 2017 May 23;114(21):5431-5436. doi: 10.1073/pnas.1617035114. Epub 2017 Apr 10.
2
NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors.NPAS1-ARNT 和 NPAS3-ARNT 的晶体结构表明 bHLH-PAS 家族是多配体结合的转录因子。
Elife. 2016 Oct 26;5:e18790. doi: 10.7554/eLife.18790.
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Reciprocal Regulation between the Circadian Clock and Hypoxia Signaling at the Genome Level in Mammals.哺乳动物基因组水平上生物钟与低氧信号的相互调控
Cell Metab. 2017 Jan 10;25(1):73-85. doi: 10.1016/j.cmet.2016.09.009. Epub 2016 Oct 20.
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Circadian Clock Interaction with HIF1α Mediates Oxygenic Metabolism and Anaerobic Glycolysis in Skeletal Muscle.昼夜节律时钟与HIF1α的相互作用介导骨骼肌中的有氧代谢和无氧糖酵解。
Cell Metab. 2017 Jan 10;25(1):86-92. doi: 10.1016/j.cmet.2016.09.010. Epub 2016 Oct 20.
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Rhythmic Oxygen Levels Reset Circadian Clocks through HIF1α.节律性氧水平通过 HIF1α 重置生物钟。
Cell Metab. 2017 Jan 10;25(1):93-101. doi: 10.1016/j.cmet.2016.09.014. Epub 2016 Oct 20.
6
Targeting renal cell carcinoma with a HIF-2 antagonist.用低氧诱导因子-2拮抗剂靶向治疗肾细胞癌。
Nature. 2016 Nov 3;539(7627):112-117. doi: 10.1038/nature19796. Epub 2016 Sep 5.
7
Structural integration in hypoxia-inducible factors.缺氧诱导因子的结构整合。
Nature. 2015 Aug 20;524(7565):303-8. doi: 10.1038/nature14883. Epub 2015 Aug 5.
8
The aryl hydrocarbon receptor: multitasking in the immune system.芳香烃受体：在免疫系统中的多重任务。
Annu Rev Immunol. 2014;32:403-32. doi: 10.1146/annurev-immunol-032713-120245.
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Regulating the ARNT/TACC3 axis: multiple approaches to manipulating protein/protein interactions with small molecules.调控 ARNT/TACC3 轴：用小分子操纵蛋白质/蛋白质相互作用的多种方法。
ACS Chem Biol. 2013 Mar 15;8(3):626-35. doi: 10.1021/cb300604u. Epub 2012 Dec 26.
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Intermolecular recognition revealed by the complex structure of human CLOCK-BMAL1 basic helix-loop-helix domains with E-box DNA.人 CLOCK-BMAL1 基本螺旋-环-螺旋结构域与 E 盒 DNA 复合物结构揭示的分子间识别
Cell Res. 2013 Feb;23(2):213-24. doi: 10.1038/cr.2012.170. Epub 2012 Dec 11.
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