Yilmaz U
Klinik für Diagnostische und Interventionelle Neuroradiologie, Universitätsklinikum des Saarlandes, Kirrberger Straße 1, 66424, Homburg/Saar, Deutschland.
Radiologe. 2017 Jun;57(6):438-442. doi: 10.1007/s00117-017-0256-5.
Metabolic disorders of the brain often present a particular challenge for the neuroradiologist, since the disorders are rare, changes on conventional MR are often non-specific and there are numerous differential diagnoses for the white substance lesions.
As a complementary method to conventional brain MRI, MR spectroscopy may help to reduce the scope of the differential diagnosis. Entities with specific MR spectroscopy patterns are Canavan disease, maple syrup urine disease, nonketotic hyperglycinemia and creatine deficiency.
脑部代谢紊乱对神经放射科医生来说往往是一项特殊挑战，因为这些紊乱较为罕见，常规磁共振成像（MR）上的变化通常不具有特异性，且白质病变存在众多鉴别诊断。
作为常规脑部磁共振成像（MRI）的补充方法，磁共振波谱成像（MR spectroscopy）可能有助于缩小鉴别诊断范围。具有特定磁共振波谱成像模式的疾病有卡纳万病、枫糖尿症、非酮症高甘氨酸血症和肌酸缺乏症。
