• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

药品的内源性与外源性仿制药参考定价

Endogenous versus exogenous generic reference pricing for pharmaceuticals.

作者信息

Antoñanzas F, Juárez-Castelló C A, Rodríguez-Ibeas R

机构信息

Department of Economics, University of La Rioja, 26004, Logroño, Spain.

出版信息

Int J Health Econ Manag. 2017 Dec;17(4):413-432. doi: 10.1007/s10754-017-9216-x. Epub 2017 May 15.

DOI:10.1007/s10754-017-9216-x
PMID:28508248
Abstract

In this paper we carry out a vertical differentiation duopoly model applied to pharmaceutical markets to analyze how endogenous and exogenous generic reference pricing influence competition between generic and branded drugs producers. Unlike the literature, we characterize for the exogenous case the equilibrium prices for all feasible relevant reference prices. Competition is enhanced after the introduction of a reference pricing system. We also compare both reference pricing systems on welfare grounds, assuming two different objective functions for health authorities: (i) standard social welfare and (ii) gross consumer surplus net of total pharmaceutical expenditures. We show that regardless of the objective function, health authorities will never choose endogenous reference pricing. When health authorities are paternalistic, the exogenous reference price that maximizes standard social welfare is such that the price of the generic drug is the reference price while the price of the branded drug is higher than the reference price. When health authorities are not paternalistic, the optimal exogenous reference price is such that the price of the branded drug is the reference price while the price of the generic drug is lower than the reference price.

摘要

在本文中,我们构建了一个应用于药品市场的垂直差异化双头垄断模型,以分析内生和外生仿制药参考定价如何影响仿制药和品牌药生产商之间的竞争。与现有文献不同的是,我们针对外生情况,刻画了所有可行相关参考价格下的均衡价格。引入参考定价系统后竞争加剧。我们还基于福利理由比较了这两种参考定价系统,假定卫生当局有两种不同的目标函数:(i)标准社会福利,以及(ii)扣除药品总支出后的消费者总剩余。我们表明,无论目标函数如何,卫生当局永远不会选择内生参考定价。当卫生当局具有家长式作风时,使标准社会福利最大化的外生参考价格是仿制药价格为参考价格,而品牌药价格高于参考价格。当卫生当局不具有家长式作风时,最优外生参考价格是品牌药价格为参考价格,而仿制药价格低于参考价格。

相似文献

1
Endogenous versus exogenous generic reference pricing for pharmaceuticals.药品的内源性与外源性仿制药参考定价
Int J Health Econ Manag. 2017 Dec;17(4):413-432. doi: 10.1007/s10754-017-9216-x. Epub 2017 May 15.
2
Impact of European pharmaceutical price regulation on generic price competition: a review.欧洲药品价格管制对仿制药价格竞争的影响:综述。
Pharmacoeconomics. 2010;28(8):649-63. doi: 10.2165/11535360-000000000-00000.
3
Reference pricing with endogenous generic entry.具有内生仿制药进入的参考定价
J Health Econ. 2016 Dec;50:312-329. doi: 10.1016/j.jhealeco.2016.04.003. Epub 2016 Jun 8.
4
Optimal price regulations in international pharmaceutical markets with generic competition.具有仿制药竞争的国际药品市场中的最优价格规制。
J Health Econ. 2020 May;71:102315. doi: 10.1016/j.jhealeco.2020.102315. Epub 2020 Apr 6.
5
Competition and the Reference Pricing Scheme for pharmaceuticals.药品竞争与参考定价机制。
J Health Econ. 2011 Dec;30(6):1137-49. doi: 10.1016/j.jhealeco.2011.08.010. Epub 2011 Sep 3.
6
Do higher-priced generic medicines enjoy a competitive advantage under reference pricing?高价仿制药在参考定价制度下是否具有竞争优势?
Appl Health Econ Health Policy. 2012 Nov 1;10(6):441-51. doi: 10.1007/BF03261878.
7
OSTEOPOROSIS DRUGS MARKETED IN THE UNITED STATES: GENERIC COMPETITION, PRICING STRUCTURE, AND DISPERSION AMONG PAYERS.在美国销售的骨质疏松症药物:仿制药竞争、定价结构及支付方之间的差异
Int J Technol Assess Health Care. 2016 Jan;32(6):385-392. doi: 10.1017/S0266462316000623. Epub 2017 Jan 9.
8
Price competition in pharmaceuticals - Evidence from 1303 Swedish markets.药品价格竞争 - 来自 1303 个瑞典市场的证据。
J Health Econ. 2018 Sep;61:1-12. doi: 10.1016/j.jhealeco.2018.06.009. Epub 2018 Jun 30.
9
Costs of paying higher prices for equivalent effects on the Pharmaceutical Benefits Scheme.在药品福利计划中为同等效果支付更高价格的成本。
Aust Health Rev. 2017 Mar;41(1):1-6. doi: 10.1071/AH15122.
10
Reference pricing of pharmaceuticals.药品参考定价
J Health Econ. 2007 May 1;26(3):613-42. doi: 10.1016/j.jhealeco.2006.11.003. Epub 2006 Dec 22.

本文引用的文献

1
Reference pricing in the presence of pseudo-generics.存在伪仿制药情况下的参考定价
Int J Health Econ Manag. 2015 Sep;15(3):281-305. doi: 10.1007/s10754-015-9165-1. Epub 2015 Feb 1.
2
The impact of generic reference pricing in Italy, a decade on.意大利通用参考定价的影响:十年回顾。
Eur J Health Econ. 2013 Dec;14(6):959-69. doi: 10.1007/s10198-012-0442-3. Epub 2012 Nov 25.
3
The impact of reference-pricing systems in Europe: a literature review and case studies.欧洲参考定价制度的影响:文献综述和案例研究。
Expert Rev Pharmacoecon Outcomes Res. 2011 Dec;11(6):729-37. doi: 10.1586/erp.11.70.
4
Competition and the Reference Pricing Scheme for pharmaceuticals.药品竞争与参考定价机制。
J Health Econ. 2011 Dec;30(6):1137-49. doi: 10.1016/j.jhealeco.2011.08.010. Epub 2011 Sep 3.
5
Effects of reference pricing in pharmaceutical markets: a review.药品市场参考定价的影响:综述
Pharmacoeconomics. 2011 Jan;29(1):17-33. doi: 10.2165/11537860-000000000-00000.
6
Reference pricing and firms' pricing strategies.参考定价与企业定价策略。
J Health Econ. 2009 Jan;28(1):176-97. doi: 10.1016/j.jhealeco.2008.09.006. Epub 2008 Oct 4.
7
Reference pricing of pharmaceuticals.药品参考定价
J Health Econ. 2007 May 1;26(3):613-42. doi: 10.1016/j.jhealeco.2006.11.003. Epub 2006 Dec 22.