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奇美拉分枝杆菌左心室辅助装置感染

Mycobacterium chimaera left ventricular assist device infections.

作者信息

Balsam Leora B, Louie Eddie, Hill Fred, Levine Jamie, Phillips Michael S

机构信息

Department of Cardiothoracic Surgery, NYU-Langone Medical Center, New York, New York.

Division of Infectious Diseases, NYU-Langone Medical Center, New York, New York.

出版信息

J Card Surg. 2017 Jun;32(6):402-404. doi: 10.1111/jocs.13150. Epub 2017 May 15.

Abstract

A global outbreak of invasive Mycobacterium chimaera infections after cardiac surgery has recently been linked to bioaerosols from contaminated heater-cooler units. The majority of cases have occurred after valvular surgery or aortic graft surgery and nearly half have resulted in death. To date, infections in patients with left ventricular assist devices (LVADs) have not been characterized in the literature. We report two cases of device-associated M. chimaera infection in patients with continuous-flow LVADs and describe challenges related to diagnosis and management in this population.

摘要

近期,心脏手术后侵袭性嵌合体分枝杆菌感染的全球暴发与受污染的心脏体外循环机产生的生物气溶胶有关。大多数病例发生在瓣膜手术或主动脉移植手术后,近半数病例导致死亡。迄今为止,左心室辅助装置(LVAD)患者的感染情况在文献中尚无描述。我们报告了两例连续血流LVAD患者发生的与装置相关的嵌合体分枝杆菌感染病例,并描述了该人群在诊断和管理方面面临的挑战。

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