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奇美拉分枝杆菌左心室辅助装置感染

Mycobacterium chimaera left ventricular assist device infections.

作者信息

Balsam Leora B, Louie Eddie, Hill Fred, Levine Jamie, Phillips Michael S

机构信息

Department of Cardiothoracic Surgery, NYU-Langone Medical Center, New York, New York.

Division of Infectious Diseases, NYU-Langone Medical Center, New York, New York.

出版信息

J Card Surg. 2017 Jun;32(6):402-404. doi: 10.1111/jocs.13150. Epub 2017 May 15.

DOI:10.1111/jocs.13150
PMID:28508409
Abstract

A global outbreak of invasive Mycobacterium chimaera infections after cardiac surgery has recently been linked to bioaerosols from contaminated heater-cooler units. The majority of cases have occurred after valvular surgery or aortic graft surgery and nearly half have resulted in death. To date, infections in patients with left ventricular assist devices (LVADs) have not been characterized in the literature. We report two cases of device-associated M. chimaera infection in patients with continuous-flow LVADs and describe challenges related to diagnosis and management in this population.

摘要

近期,心脏手术后侵袭性嵌合体分枝杆菌感染的全球暴发与受污染的心脏体外循环机产生的生物气溶胶有关。大多数病例发生在瓣膜手术或主动脉移植手术后,近半数病例导致死亡。迄今为止,左心室辅助装置(LVAD)患者的感染情况在文献中尚无描述。我们报告了两例连续血流LVAD患者发生的与装置相关的嵌合体分枝杆菌感染病例,并描述了该人群在诊断和管理方面面临的挑战。

相似文献

1
Mycobacterium chimaera left ventricular assist device infections.奇美拉分枝杆菌左心室辅助装置感染
J Card Surg. 2017 Jun;32(6):402-404. doi: 10.1111/jocs.13150. Epub 2017 May 15.
2
Healthcare-Associated Mycobacterium chimaera Infection Subsequent to Heater-Cooler Device Exposure During Cardiac Surgery.心脏手术期间接触热交换器设备后发生的医疗保健相关嵌合体分枝杆菌感染
J Cardiothorac Vasc Anesth. 2017 Oct;31(5):1831-1835. doi: 10.1053/j.jvca.2017.05.028. Epub 2017 May 17.
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Global outbreak of severe Mycobacterium chimaera disease after cardiac surgery: a molecular epidemiological study.全球心脏手术后感染罕见分枝杆菌病的爆发:一项分子流行病学研究。
Lancet Infect Dis. 2017 Oct;17(10):1033-1041. doi: 10.1016/S1473-3099(17)30324-9. Epub 2017 Jul 12.
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Mycobacterium abscessus Left Ventricle Assist Device Driveline Infections: An Emerging Pathogen?脓肿分枝杆菌左心室辅助装置驱动线感染:一种新出现的病原体?
Transpl Infect Dis. 2018 Oct;20(5):e12957. doi: 10.1111/tid.12957. Epub 2018 Jun 28.
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Mycobacterium chimaera Infections Related to the Heater-Cooler Unit Outbreak: A Guide to Diagnosis and Management.奇美拉分枝杆菌感染与热交换器单元爆发有关:诊断和管理指南。
Clin Infect Dis. 2019 Mar 19;68(7):1244-1250. doi: 10.1093/cid/ciy789.
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Current management of left ventricular assist device erosion.
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Mycobacterium chimaera Infections Associated With Contaminated Heater-Cooler Devices for Cardiac Surgery: Outbreak Management.加热-冷却设备污染导致的奇美拉分枝杆菌感染:暴发管理。
Clin Infect Dis. 2017 Aug 15;65(4):669-674. doi: 10.1093/cid/cix368.
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Reemergence of Mycobacterium chimaera in Heater-Cooler Units despite Intensified Cleaning and Disinfection Protocol.尽管强化了清洁和消毒方案,分枝杆菌仍在热交换器中再次出现。
Emerg Infect Dis. 2016 Oct;22(10):1830-3. doi: 10.3201/eid2210.160925.
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Microbiological problems and biofilms associated with Mycobacterium chimaera in heater-cooler units used for cardiopulmonary bypass.与心肺旁路中使用的热交换器相关的加热冷却装置中,拟分枝杆菌的微生物问题和生物膜。
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Rapid detection of invasive Mycobacterium chimaera disease via a novel plasma-based next-generation sequencing test.新型血浆二代测序检测快速检测侵袭性丘氏分枝杆菌病。
BMC Infect Dis. 2019 May 2;19(1):371. doi: 10.1186/s12879-019-4001-8.

引用本文的文献

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The State-of-the-Art of Infections and the Causal Link with Health Settings: A Systematic Review.感染的最新情况及其与健康环境的因果关系:一项系统综述。
Healthcare (Basel). 2024 Sep 6;12(17):1788. doi: 10.3390/healthcare12171788.
2
Long-Term Follow-Up after Mycobacterium Chimaera Infection Following Cardiac Surgery: Single-Center Experience.心脏手术后感染奇美拉分枝杆菌的长期随访:单中心经验
J Clin Med. 2023 Jan 26;12(3):948. doi: 10.3390/jcm12030948.
3
Pharmacologic Management of Infections: A Primer for Clinicians.感染的药物治疗:临床医生入门指南
Open Forum Infect Dis. 2022 Jun 15;9(7):ofac287. doi: 10.1093/ofid/ofac287. eCollection 2022 Jul.
4
Nontuberculous Mycobacterial Infections Associated With Left Ventricular Assist Devices in 3 Patients.3 例与左心室辅助装置相关的非结核分枝杆菌感染。
Tex Heart Inst J. 2022 Jul 1;49(4). doi: 10.14503/THIJ-20-7498.
5
Mycobacterium abscessus Infection in Left Ventricular Assist Device (LVAD): A Case Series.左心室辅助装置(LVAD)中的脓肿分枝杆菌感染:病例系列
Cureus. 2021 Jun 17;13(6):e15718. doi: 10.7759/cureus.15718. eCollection 2021 Jun.
6
Improving Decreased Heater-Cooler Efficiency as a Result of Heater-Cooler Infection Control Strategy.通过热交换器感染控制策略提高降低的热交换器效率
J Extra Corpor Technol. 2019 Jun;51(2):73-77.
7
Skin and Soft Tissue Infections Due to Nontuberculous Mycobacteria.非结核分枝杆菌引起的皮肤和软组织感染
Curr Infect Dis Rep. 2018 Mar 19;20(4):6. doi: 10.1007/s11908-018-0611-3.