Rehak Zdenek, Sprlakova-Pukova Andrea, Kazda Tomas, Fojtik Zdenek, Vargova Lenka, Nemec Petr
1 Department of Nuclear Medicine and PET Center, Masaryk Memorial Cancer Institute, Brno, Czech Republic.
2 Regional Center for Applied Molecular Oncology (RECAMO), Masaryk Memorial Cancer Institute, Brno, Czech Republic.
Br J Radiol. 2017 Aug;90(1076):20170198. doi: 10.1259/bjr.20170198. Epub 2017 Jun 16.
Polymyalgia rheumatica (PMR) is one of the inflammatory rheumatic diseases that can potentially be detected by positron emission tomography/CT. High fluorine-18 fludeoxyglucose (F-FDG) accumulation around the shoulders, sternoclavicular and hip joints are the most common pre-treatment features of patients with PMR. Another common sign is increased F-FDG uptake in extra-articular regions between columnal spinous processes, near ischial tuberosities and in the praepubic area. Some patients also present with high F-FDG uptake in main arteries, corresponding to the characteristics of giant cell arteritis. It is possible to observe a decrease or even a disappearance of F-FDG uptake after effective therapy, an event which may be useful for the monitoring of treatment as well as for detection of PMR relapse.
风湿性多肌痛(PMR)是一种可通过正电子发射断层扫描/计算机断层扫描(PET/CT)潜在检测出的炎性风湿性疾病。肩部、胸锁关节和髋关节周围高氟-18氟脱氧葡萄糖(F-FDG)积聚是PMR患者最常见的治疗前特征。另一个常见体征是在椎体棘突之间、坐骨结节附近和耻骨前区域的关节外区域F-FDG摄取增加。一些患者还表现出主动脉中F-FDG摄取增高,这与巨细胞动脉炎的特征相符。有效治疗后可观察到F-FDG摄取减少甚至消失,这一情况可能对治疗监测以及PMR复发检测有用。