加快低收入和中等收入国家优化抗逆转录病毒治疗的可及性并扩大其规模：呼吁采取协调一致的端到端方法。
Accelerating access and scale-up of optimized ART in low-income and middle-income countries: a call for a coordinated end-to-end approach.
作者信息
Harris Emily, Pérez-Casas Carmen, Barnhart Matthew, Lin Amy H, Ferris Danielle, Ajose Olawale, Burgess Emma K, Fowler Rachel
机构信息
aUNITAID, Geneva, Switzerland bUnited States Agency for International Development (USAID), Office of HIV/AIDS cUnited States Agency for International Development (USAID), Center for Accelerating Innovation and Impact, Washington, District of Columbia dUnited States Agency for International Development (USAID), Office of the Assistant Administrator for Global Health, USA.
出版信息
Curr Opin HIV AIDS. 2017 Jul;12(4):383-389. doi: 10.1097/COH.0000000000000383.
PURPOSE OF REVIEW
To discuss how aligning the collective power of scientists, regulators, drug companies, donors, implementers and advocates to achieve a single goal - accelerating access to simpler, safer, more robust and more affordable HIV treatment - can rapidly advance antiretroviral optimization efforts and enable scale-up.
RECENT FINDINGS
Harmonization of traditionally sequential processes can address the delays commonly experienced in introducing new products to low-income and middle-income countries, by facilitating an 'end-to-end' approach that mitigates risk and encourages early planning for all aspects of product introduction.
SUMMARY
Planning with the 'end-in-mind' can facilitate healthy markets, benefit the application of new technologies, and accelerate the development of improved products in parallel (versus traditionally sequential efforts).
综述目的
探讨如何整合科学家、监管机构、制药公司、捐赠者、实施者和倡导者的集体力量以实现单一目标——加速获得更简单、更安全、更有效且更经济实惠的艾滋病毒治疗方法，从而迅速推进抗逆转录病毒治疗的优化工作并实现扩大规模。
最新研究结果
通过采用一种“端到端”方法来减轻风险并鼓励对产品引进的各个方面进行早期规划，协调传统的顺序流程可以解决在向低收入和中等收入国家引入新产品时常见的延误问题。
总结
以“心中有目标”的方式进行规划可以促进健康的市场，有利于新技术的应用，并加速改进产品的并行开发（与传统的顺序式努力相比）。
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