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自发性冠状动脉夹层:发病机制、临床表现、治疗及预后综述

Spontaneous Coronary Artery Dissection: A Review of Pathogenesis, Presentations, Treatment, and Outcomes.

作者信息

Afzal Aasim, Sarmast Syed, Choi James W, McCullough Peter A, Schussler Jeffrey M

机构信息

Baylor University Medical Center, Division of Cardiology, Dallas, TX; Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, TX.

Baylor University Medical Center, Division of Cardiology, Dallas, TX.

出版信息

Rev Cardiovasc Med. 2017;18(1):29-36. doi: 10.3909/ricm0842.

DOI:10.3909/ricm0842
PMID:28509891
Abstract

Spontaneous coronary artery dissection (SCAD) is a rare cause of acute coronary syndromes and sudden cardiac death. The epidemiology, pathogenesis, and optimal approaches to diagnosis and management are poorly understood. Additionally, SCAD as a syndrome is commonly under-recognized and its prognosis is not well studied. Guidelines on management of SCAD have not yet been established. We present three cases of SCAD that varied in their clinical presentation and describe the different management strategies utilized. This is followed by a review of the clinical features, epidemiology, prognosis, and potential treatment strategies for patients presenting with SCAD.

摘要

自发性冠状动脉夹层(SCAD)是急性冠状动脉综合征和心源性猝死的罕见病因。其流行病学、发病机制以及诊断和管理的最佳方法目前仍知之甚少。此外,SCAD作为一种综合征通常未得到充分认识,其预后也未得到充分研究。目前尚未制定关于SCAD管理的指南。我们报告了3例临床表现各异的SCAD病例,并描述了所采用的不同管理策略。随后对SCAD患者的临床特征、流行病学、预后及潜在治疗策略进行综述。

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