Lee Regina, Ben-Dor Itsik
Georgetown University Hospital, Washington, D.C.; MedStar Heart and Vascular Institute, MedStar Washington Hospital Center, Washington, D.C..
MedStar Heart and Vascular Institute, MedStar Washington Hospital Center, Washington, D.C.
Cardiovasc Revasc Med. 2017 Oct-Nov;18(7):544-548. doi: 10.1016/j.carrev.2017.05.008. Epub 2017 May 12.
Spontaneous coronary artery dissection (SCAD) is becoming widely recognized as an important cause of myocardial infarction, particularly in younger women. Tendency toward conservative management has been primarily based on observational data. Intervention is recommended when coronary blood flow is compromised and high risk features such as left main involvement, ongoing ischemia, or hemodynamic or electrical instability are present. Unlike the atherosclerotic process where the superiority of stenting compared with plain old balloon angioplasty has been established in the acute setting, randomized studies for revascularization strategies for spontaneous coronary dissection are currently lacking. We highlight 4 cases of SCAD from our institution, review the literature with regard to percutaneous revascularization in this population, and propose a step-wise algorithm for percutaneous intervention strategies in managing higher-risk SCAD.
自发性冠状动脉夹层(SCAD)正日益被广泛认为是心肌梗死的一个重要原因,尤其是在年轻女性中。保守治疗的倾向主要基于观察性数据。当冠状动脉血流受到损害且存在左主干受累、持续性缺血或血流动力学或电不稳定等高风险特征时,建议进行干预。与动脉粥样硬化过程不同,在急性情况下,支架置入术相对于普通球囊血管成形术的优势已经确立,而目前缺乏关于自发性冠状动脉夹层血运重建策略的随机研究。我们重点介绍了我院的4例SCAD病例,回顾了该人群经皮血运重建的相关文献,并提出了一种用于管理高风险SCAD的经皮干预策略的逐步算法。