Stover John, Rosen James E, Carvalho Maria Nadia, Korenromp Eline L, Friedman Howard S, Cogan Matthew, Deperthes Bidia
Avenir Health, Glastonbury, Connecticut, United States of America.
United Nations Population Fund (UNFPA), New York City, New York, United States of America.
PLoS One. 2017 May 16;12(5):e0177108. doi: 10.1371/journal.pone.0177108. eCollection 2017.
When used correctly and consistently, the male condom offers triple protection from unintended pregnancy and the transmission of sexually transmitted infections (STIs) and human immunodeficiency virus (HIV). However, with health funding levels stagnant or falling, it is important to understand the cost and health impact associated with prevention technologies. This study is one of the first to attempt to quantify the cost and combined health impact of condom use, as a means to prevent unwanted pregnancy and to prevent transmission of STIs including HIV. This paper describes the analysis to make the case for investment in the male condom, including the cost, impact and cost-effectiveness by three scenarios (low in which 2015 condom use levels are maintained; medium in which condom use trends are used to predict condom use from 2016-2030; and high in which condom use is scaled up, as part of a package of contraceptives, to meet all unmet need for family planning by 2030 and to 90% for HIV and STI prevention by 2016) for 81 countries from 2015-2030. An annual gap between current and desired use of 10.9 billion condoms was identified (4.6 billion for family planning and 6.3 billion for HIV and STIs). Under a high scenario that completely reduces that gap between current and desired use of 10.9 billion condoms, we found that by 2030 countries could avert 240 million DALYs. The additional cost in the 81 countries through 2030 under the medium scenario is $1.9 billion, and $27.5 billion under the high scenario. Through 2030, the cost-effectiveness ratios are $304 per DALY averted for the medium and $115 per DALY averted for the high scenario. Under the three scenarios described above, our analysis demonstrates the cost-effectiveness of the male condom in preventing unintended pregnancy and HIV and STI new infections. Policy makers should increase budgets for condom programming to increase the health return on investment of scarce resources.
正确且持续使用男用避孕套可提供三重保护,防止意外怀孕、性传播感染(STIs)和人类免疫缺陷病毒(HIV)的传播。然而,由于卫生资金水平停滞不前或不断下降,了解与预防技术相关的成本和健康影响非常重要。本研究是首批试图量化避孕套使用的成本和综合健康影响的研究之一,以此作为预防意外怀孕和预防包括HIV在内的性传播感染的一种手段。本文描述了为支持投资男用避孕套而进行的分析,包括三种情景(低情景:维持2015年的避孕套使用水平;中情景:利用避孕套使用趋势预测2016 - 2030年的避孕套使用情况;高情景:作为一揽子避孕药具的一部分扩大避孕套使用规模,到2030年满足所有未满足的计划生育需求,到2016年预防HIV和性传播感染的比例达到90%)下2015 - 2030年81个国家的成本、影响和成本效益。研究发现,目前的避孕套使用量与预期使用量之间每年存在109亿个避孕套的差距(46亿个用于计划生育,63亿个用于预防HIV和性传播感染)。在完全消除当前与预期使用量之间109亿个避孕套差距的高情景下,我们发现到2030年各国可避免2.4亿伤残调整生命年(DALYs)。到2030年,81个国家在中情景下的额外成本为19亿美元,在高情景下为275亿美元。到2030年,中情景下每避免一个伤残调整生命年的成本效益比为304美元,高情景下为115美元。在上述三种情景下,我们的分析表明男用避孕套在预防意外怀孕以及HIV和性传播感染新感染方面具有成本效益。政策制定者应增加避孕套项目的预算,以提高稀缺资源的健康投资回报。