Ranganathan Kannan, Mathew Seema Alice, Sreena Nellimad Sreedharan, Lavanya Nagarajan
Professor and Head, Department of Oral Pathology, Ragas Dental College and Hosptal, Chennai, Tamil Nadu, India.
Senior Lecturer, Department of Oral and Maxillofacial Surgery, Ragas Dental College and Hosptal, Chennai, Tamil Nadu, India.
J Clin Diagn Res. 2017 Mar;11(3):ZD01-ZD03. doi: 10.7860/JCDR/2017/24609.9357. Epub 2017 Mar 1.
Pleomorphic lipoma is a rare, benign, soft tissue neoplasm that characteristically occurs as a subcutaneous mass in the posterior neck or upper back and rarely in the tonsillar fossa and oral cavity. Histologically, pleomorphic lipoma contains varying amounts of mature fat, areas of spindle and pleomorphic cells, floret giant cells and thick rope - like collagen in a myxoid stroma. Pleomorphic lipoma with scanty fatty elements is called the fat free variant of pleomorphic lipoma. The combination of meagre amount of fat and presence of pleomorphic elements gives a pseudosarcomatous picture under the microscope leading to misdiagnosis and over treatment. Here, we report a case of fat free pleomorphic lipoma, first of its kind in the oral cavity and discuss the diagnostic features and differential diagnosis.
多形性脂肪瘤是一种罕见的良性软组织肿瘤，其特征是作为皮下肿块出现在后颈部或上背部，很少发生在扁桃体窝和口腔。组织学上，多形性脂肪瘤含有不同数量的成熟脂肪、梭形和多形性细胞区域、花环状巨细胞以及黏液样基质中的粗绳状胶原。脂肪成分稀少的多形性脂肪瘤被称为多形性脂肪瘤的无脂肪变体。脂肪量少和多形性成分的存在在显微镜下呈现假肉瘤样表现，导致误诊和过度治疗。在此，我们报告一例口腔内首例无脂肪多形性脂肪瘤病例，并讨论其诊断特征和鉴别诊断。
