D'Antonio Antonio, Locatelli Giampiero, Liguori Giuseppina, Addesso Maria
Department of Pathologic Anatomy and Oncology, A.O.U. "San Giovanni di Dio e Ruggi d'Aragona" via S. Leonardo, Salerno, Italy.
J Cutan Aesthet Surg. 2013 Jan;6(1):51-3. doi: 10.4103/0974-2077.110101.
We herein report a rare case of pleomorphic lipoma of the tongue with a review of world literature. A 44-year-old woman presented with a nodule of the tongue that had been present for over three years. Clinical examination revealed a yellowish sub-mucosal lesion, measuring 3 cm in maximum diameter, protruding from lingual surface. A first biopsy showed a lipomatous tumour composed of mature adipocytes intermingled with myxoid areas composed of spindle uniform in size and shape and multinucleated floret-like giant cells. Spindle and giant cells were positive for CD34. A diagnosis of pleomorphic lipoma was made. In view of the benign nature of this mass, it was de-bulked rather than completely excised in order to preserve swallowing function.
我们在此报告一例罕见的舌部多形性脂肪瘤病例，并对世界文献进行综述。一名44岁女性患者舌部出现肿物已超过三年。临床检查发现一个淡黄色黏膜下病变，最大直径为3厘米，从舌表面突出。首次活检显示为脂肪瘤性肿瘤，由成熟脂肪细胞与黏液样区域混合组成，黏液样区域由大小和形状均匀的梭形细胞及多核花环状巨细胞构成。梭形细胞和巨细胞CD34呈阳性。诊断为多形性脂肪瘤。鉴于该肿物的良性性质，为保留吞咽功能，采取了减瘤而非完整切除的治疗方式。
