Aiken Abigail R A, Digol Irena, Trussell James, Gomperts Rebecca
LBJ School of Public Affairs, University of Texas at Austin, TX 78713, USA
Population Research Center, University of Texas at Austin, TX 78712, USA.
BMJ. 2017 May 16;357:j2011. doi: 10.1136/bmj.j2011.
To assess self reported outcomes and adverse events after self sourced medical abortion through online telemedicine. Population based study. Republic of Ireland and Northern Ireland, where abortion is unavailable through the formal healthcare system except in a few restricted circumstances. 1000 women who underwent self sourced medical abortion through Women on Web (WoW), an online telemedicine service, between 1 January 2010 and 31 December 2012. Successful medical abortion: the proportion of women who reported ending their pregnancy without surgical intervention. Rates of adverse events: the proportion who reported treatment for adverse events, including receipt of antibiotics and blood transfusion, and deaths reported by family members, friends, or the authorities. Care seeking for symptoms of potential complications: the frequency with which women reported experiencing symptoms of a potentially serious complication and the proportion who reported seeking medical attention as advised. In 2010-12, abortion medications (mifepristone and misoprostol) were sent to 1636 women and follow-up information was obtained for 1158 (71%). Among these, 1023 women confirmed use of the medications, and follow-up information was available for 1000. At the time women requested help from WoW, 781 (78%) were <7 weeks pregnant and 219 (22%) were 7-9 weeks pregnant. Overall, 94.7% (95% confidence interval 93.1% to 96.0%) reported successfully ending their pregnancy without surgical intervention. Seven women (0.7%, 0.3% to 1.5%) reported receiving a blood transfusion, and 26 (2.6%, 1.7% to 3.8%) reported receiving antibiotics (route of administration (IV or oral) could not be determined). No deaths resulting from the intervention were reported by family, friends, the authorities, or the media. Ninety three women (9.3%, 7.6% to 11.3%) reported experiencing any symptom for which they were advised to seek medical advice, and, of these, 87 (95%, 87.8% to 98.2%) sought attention. None of the five women who did not seek medical attention reported experiencing an adverse outcome. Self sourced medical abortion using online telemedicine can be highly effective, and outcomes compare favourably with in clinic protocols. Reported rates of adverse events are low. Women are able to self identify the symptoms of potentially serious complications, and most report seeking medical attention when advised. Results have important implications for women worldwide living in areas where access to abortion is restricted.
通过在线远程医疗评估自行获取药物流产后的自我报告结局和不良事件。基于人群的研究。爱尔兰共和国和北爱尔兰,在这些地区,除了少数受限情况外,通过正规医疗系统无法获得堕胎服务。2010年1月1日至2012年12月31日期间,1000名通过在线远程医疗服务“女性在线”(WoW)进行自行获取药物流产的女性。成功的药物流产:报告在无手术干预的情况下终止妊娠的女性比例。不良事件发生率:报告接受不良事件治疗的比例,包括接受抗生素治疗和输血,以及家庭成员、朋友或当局报告的死亡情况。因潜在并发症症状而寻求医疗护理:女性报告经历潜在严重并发症症状的频率,以及报告按建议寻求医疗护理的比例。在2010 - 2012年期间,向1636名女性发送了堕胎药物(米非司酮和米索前列醇),并获得了1158名(71%)的随访信息。其中,1023名女性确认使用了这些药物,并且有1000名的随访信息可用。在女性向WoW寻求帮助时,781名(78%)怀孕<7周,219名(22%)怀孕7 - 9周。总体而言,94.7%(95%置信区间93.1%至96.0%)报告在无手术干预的情况下成功终止妊娠。7名女性(0.7%,0.3%至1.5%)报告接受了输血,26名(2.6%,1.7%至3.8%)报告接受了抗生素治疗(给药途径(静脉注射或口服)无法确定)。家庭成员、朋友、当局或媒体均未报告因该干预导致的死亡。93名女性(9.3%,7.6%至11.3%)报告经历了任何她们被建议寻求医疗建议的症状,其中87名(95%,87.8%至98.2%)寻求了医疗护理。未寻求医疗护理的5名女性中,无人报告经历不良结局。使用在线远程医疗自行获取药物流产可能非常有效,结局与临床方案相比具有优势。报告的不良事件发生率较低。女性能够自行识别潜在严重并发症的症状,并且大多数人报告在被建议时会寻求医疗护理。研究结果对生活在堕胎受限地区的全球女性具有重要意义。