Schuh J C, Sileo L, Siegfried L M, Yuill T M
Department of Veterinary Science, University of Wisconsin, Madison 53706.
J Am Vet Med Assoc. 1986 Nov 1;189(9):993-6.
Inclusion body disease of cranes was the cause of death in 17 immature and mature cranes of 5 different species in Wisconsin. A herpesvirus of unknown origin was the apparent cause. An isolate of this herpesvirus was used to experimentally infect 3 species of cranes. Macroscopic and microscopic lesions associated with naturally acquired and experimentally induced disease were essentially identical. Multifocal hepatic and splenic necrosis was found in all cranes evaluated. Necrosis of the gastrointestinal tract, thymus, and bursa of Fabricius also was seen in some of the cranes. Eosinophilic intranuclear inclusion bodies often were commonly associated with hepatic lesions, sometimes with the splenic lesions, and rarely with the thymic or gastrointestinal tract lesions. The lesions of this inclusion body disease were similar to those reported for cranes in Austria from which a crane herpesvirus was isolated.
鹤的包涵体病是威斯康星州5种不同种类的17只未成熟和成熟鹤死亡的原因。一种来源不明的疱疹病毒显然是病因。该疱疹病毒的一个分离株被用于对3种鹤进行实验性感染。与自然感染和实验诱导疾病相关的宏观和微观病变基本相同。在所有接受评估的鹤中均发现多灶性肝坏死和脾坏死。在一些鹤中还可见胃肠道、胸腺和法氏囊坏死。嗜酸性核内包涵体常与肝脏病变相关，有时与脾脏病变相关，很少与胸腺或胃肠道病变相关。这种包涵体病的病变与奥地利报道的鹤的病变相似，奥地利曾从鹤中分离出一种鹤疱疹病毒。
