Gimbel M E, Ten Berg J M
Department of Cardiology, St. Antonius Hospital, Nieuwegein, The Netherlands.
Neth Heart J. 2017 Jul;25(7-8):409-415. doi: 10.1007/s12471-017-1002-3.
Elderly patients with an acute coronary syndrome are underrepresented in randomised controlled trials. Neither the European Society of Cardiology nor the American Heart Association/American College of Cardiology acute coronary syndrome guidelines provide specific recommendations for elderly patients. However, elderly patients are at higher thrombotic and bleeding risk compared with younger patients leading to difficulties in choosing the optimal treatment. In this review, we discuss the uncertainties we encounter in treating elderly patients with non-ST-elevation acute coronary syndrome and suggest treatment options based on the existing literature.
老年急性冠状动脉综合征患者在随机对照试验中的代表性不足。欧洲心脏病学会和美国心脏协会/美国心脏病学会的急性冠状动脉综合征指南均未针对老年患者提供具体建议。然而,与年轻患者相比,老年患者的血栓形成和出血风险更高,这导致在选择最佳治疗方案时存在困难。在本综述中,我们讨论了在治疗非ST段抬高型急性冠状动脉综合征老年患者时遇到的不确定性,并根据现有文献提出了治疗选择。