Department of Pediatrics, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea.
Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea.
J Eur Acad Dermatol Venereol. 2017 Sep;31(9):1509-1515. doi: 10.1111/jdv.14343. Epub 2017 Jun 21.
Atopic dermatitis (AD) is one of the most common allergic diseases. Its prevalence has been increasing in recent decades. Socio-economic status is well-known risk factor of allergic diseases.
This study was performed to investigate the relationship between socio-economic status and AD in Korean adults.
Data were acquired from 47 351 men and women, ≥19 years of age who participated in the Korea National Health and Nutrition Examination Surveys (KNHANES) conducted from 2007 to 2014. The presence of AD was based on self-reported physician diagnosis of AD in the Health Interview Surveys.
The prevalence of AD was 3.1%, which decreased with increasing age. In univariate analysis, adults with AD were prone to be female, younger, never-married, well educated, lower household members, and urban dwelling (all P < 0.01). Monthly family income and smoking status were not associated with the presence of AD. The prevalence of hypertension, diabetes mellitus and asthma was higher in AD subjects (all P < 0.01), while obesity was not associated with adult AD. After adjusting for confounders, logistic regression analysis showed female sex (adjusted odds ratio [aOR]: 1.483, 95% CI: 1.268-1.734), age (P < 0.01), marital status (Single: aOR: 1.307, 95% CI: 1.012-1.690; Never-married: aOR: 1.938, 95% CI: 1.513-2.482), urban residence (aOR: 1.281, 95% CI: 1.045-1.569) and asthma (aOR: 1.788, 95% CI: 1.416-2.258) were associated with higher prevalence of AD (all P < 0.01).
Female sex, age, marital status, urban residence, and the presence of asthma are important risk factors of the prevalence of AD in Korean adults.
特应性皮炎(AD)是最常见的过敏性疾病之一。近几十年来,其患病率一直在上升。社会经济地位是已知的过敏性疾病的危险因素。
本研究旨在探讨韩国成年人社会经济地位与 AD 之间的关系。
数据来自 2007 年至 2014 年参加韩国国家健康和营养检查调查(KNHANES)的 47351 名年龄≥19 岁的男性和女性。AD 的存在是基于健康访谈调查中自我报告的医生诊断 AD。
AD 的患病率为 3.1%,随年龄增长而降低。在单因素分析中,患有 AD 的成年人更倾向于女性、年龄较小、未婚、受教育程度较高、家庭人口较少且居住在城市(均 P<0.01)。家庭月收入和吸烟状况与 AD 的发生无关。AD 患者高血压、糖尿病和哮喘的患病率较高(均 P<0.01),而肥胖与成人 AD 无关。在调整混杂因素后,Logistic 回归分析显示女性(调整优势比[aOR]:1.483,95%置信区间[CI]:1.268-1.734)、年龄(P<0.01)、婚姻状况(单身:aOR:1.307,95%CI:1.012-1.690;未婚:aOR:1.938,95%CI:1.513-2.482)、城市居住(aOR:1.281,95%CI:1.045-1.569)和哮喘(aOR:1.788,95%CI:1.416-2.258)与 AD 患病率升高相关(均 P<0.01)。
女性、年龄、婚姻状况、城市居住和哮喘是韩国成年人 AD 患病率的重要危险因素。