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韩国大田市 2015 年中东呼吸综合征医院感染暴发。

Hospital Outbreaks of Middle East Respiratory Syndrome, Daejeon, South Korea, 2015.

出版信息

Emerg Infect Dis. 2017 Jun;23(6):898-905. doi: 10.3201/eid2306.160120.

DOI:10.3201/eid2306.160120
PMID:28516865
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5443424/
Abstract

From May through July 2015, a total of 26 cases of Middle East Respiratory Syndrome were reported from 2 hospitals in Daejeon, South Korea, including 1 index case and 25 new cases. We examined the epidemiologic features of these cases and found an estimated median incubation period of 6.1 days (8.8 days in hospital A and 4.6 days in hospital B). The overall attack rate was 3.7% (4.7% in hospital A and 3.0% in hospital B), and the attack rates among inpatients and caregivers in the same ward were 12.3% and 22.5%, respectively. The overall case-fatality rate was 44.0% (28.6% in hospital A and 63.6% in hospital B). The use of cohort quarantine may have played a role in preventing community spread, but additional transmission occurred among members of the hospital cohort quarantined together. Caregivers may have contributed in part to the transmission.

摘要

2015 年 5 月至 7 月,韩国大田市的两家医院共报告了 26 例中东呼吸综合征病例,包括 1 例输入性病例和 25 例本地感染病例。我们对这些病例的流行病学特征进行了分析,估计潜伏期中位数为 6.1 天(A 医院为 8.8 天,B 医院为 4.6 天)。总感染率为 3.7%(A 医院为 4.7%,B 医院为 3.0%),同一病房住院患者和陪护人员的感染率分别为 12.3%和 22.5%。总病死率为 44.0%(A 医院为 28.6%,B 医院为 63.6%)。采用队列隔离的方法可能有助于防止社区传播,但在集中隔离的医院队列人群中仍发生了后续传播。陪护人员可能在一定程度上促成了传播。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c00/5443424/aa83a863c1a8/16-0120-F3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c00/5443424/6f854a07bdb2/16-0120-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c00/5443424/c154c95d06c4/16-0120-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c00/5443424/aa83a863c1a8/16-0120-F3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c00/5443424/6f854a07bdb2/16-0120-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c00/5443424/c154c95d06c4/16-0120-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c00/5443424/aa83a863c1a8/16-0120-F3.jpg

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