Massillon-Jl G, Domingo-Muñoz I, Díaz-Aguirre P
Instituto de Fisica, Universidad Nacional Autónoma de México, DF, Mexico.
Hospital San Javier, Mexico.
Med Phys. 2012 Jun;39(6Part11):3730. doi: 10.1118/1.4735178.
To investigate the accuracy of the absorbed dose measured with Gafchromic EBT2 film in low-energy photon radiation fieldsMethods: Six EBT2 film (lot # F06110901) pieces (1cm ) per dose were exposed to x-rays of 50 kV, 80 kV, 120 kV and 60Co gamma rays from a Leksell Gamma Knife at dose values from 50 mGy to 100 Gy. The x-ray beams were calibrated following the AAPMTG-61 protocol using ionization chambers calibrated at NIST or Wisconsin University depending on the beam quality, while the 60Co gamma was calibrated in water using MD-V2-55 film. Each film piece was scanned once using a HP Scanjet 7650 document flatbed scanner in transmission mode, 48-bit color at 300 dpi spatial-resolution. The data analysis was made through the ImageJ. The measured light intensity for the red channel with its associate standard deviation was used to evaluate the netOD and its standard combined uncertainty. The absorbed dose as a function of the netOD was fitted using the logistic model and the relative combined uncertainties were evaluated for each energy photon beam.
EBT2 film response curve depends on the low-energy photons and the degree of energy-dependence is a function of absorbed dose. The absorbed dose relative combined uncertainty as a function of the absorbed dose indicates that the minimum absorbed dose limit is also energy dependent. Lower is the energy photon; more accurate is the measurement at low dose value. This can be explain by the fact that comparing to high energy photons, low energy photons can produce locally enough ionization density to create more color centre in the same film area.
Minimum absorbed dose limit of Gafchromic EBT2 films were found to be energy dependent. The response curve depends on the low-energy photons and the degree of energy-dependence is a function of absorbed dose This work is partially supported by DGAPA-UNAM grant IN102610 and Conacyt Mexico grant 127409.
研究在低能光子辐射场中使用Gafchromic EBT2薄膜测量吸收剂量的准确性。
将每剂量6片EBT2薄膜(批次号F06110901,尺寸为1cm)暴露于来自Leksell伽马刀的50 kV、80 kV、120 kV的X射线和60Co伽马射线,剂量值范围为50 mGy至100 Gy。根据AAPMTG - 61协议,使用在NIST或威斯康星大学校准的电离室对X射线束进行校准,具体取决于束流质量,而60Co伽马射线在水中使用MD - V2 - 55薄膜进行校准。每个薄膜片使用HP Scanjet 7650文档平板扫描仪在透射模式下扫描一次,空间分辨率为300 dpi,48位彩色。通过ImageJ进行数据分析。使用红色通道的测量光强度及其相关标准偏差来评估净光密度(netOD)及其标准合成不确定度。使用逻辑模型拟合吸收剂量作为净光密度的函数,并评估每个能量光子束的相对合成不确定度。
EBT2薄膜响应曲线取决于低能光子,能量依赖程度是吸收剂量的函数。吸收剂量相对合成不确定度作为吸收剂量的函数表明,最小吸收剂量限值也与能量有关。光子能量越低,在低剂量值下的测量越准确。这可以通过以下事实来解释:与高能光子相比,低能光子可以在相同的薄膜区域产生足够的局部电离密度,从而产生更多的色心。
发现Gafchromic EBT2薄膜的最小吸收剂量限值与能量有关。响应曲线取决于低能光子,能量依赖程度是吸收剂量的函数。本研究部分得到了墨西哥国立自治大学(DGAPA - UNAM)资助项目IN102610以及墨西哥国家科学技术委员会(Conacyt)资助项目127409的支持。