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肌少症是独立生活的日本老年人跌倒的一个风险因素:GAINA 研究的一项为期 2 年的前瞻性队列研究。

Sarcopenia is a risk factor for falling in independently living Japanese older adults: A 2-year prospective cohort study of the GAINA study.

机构信息

Rehabilitation Division, Tottori University Hospital, Yonago, Tottori, Japan.

Faculty of Medicine, School of Health Science, Tottori University, Yonago, Tottori, Japan.

出版信息

Geriatr Gerontol Int. 2017 Nov;17(11):2124-2130. doi: 10.1111/ggi.13047. Epub 2017 May 18.

Abstract

AIM

The purpose of the present study was to investigate whether sarcopenia was associated with future falls in the general Japanese older population.

METHODS

This study was a 2-year prospective observational study. Participants were recruited from individuals who had an annual town-sponsored medical check-up and had not received nursing care. The inclusion criteria for participants in our study were: (i) agreement to participate; (ii) living independently; and (iii) the ability to walk to where the survey was carried out and to provide self-reported data. A total of 223 residents (82 men, 141 women) participated in the baseline assessment in the study. Demographic information, previous fall history, locomotive syndrome, body function and structural measurements and pain at the knee and/or lumber spine were assessed. The Asian Working Group for Sarcopenia algorithm was used to classify the presence of sarcopenia, and assess the history of falling when the participant received their annual medical check-up.

RESULTS

A total of 162 participants had an annual follow-up assessment, 50 of whom (30.8%) fell at least once during the 2-year observational period after baseline assessment. Previous falling history, prevalence of locomotive syndrome, sarcopenia and pain were significantly higher in participants who had fallen compared with participants who had not. Multiple logistic regression analysis showed the prevalence of sarcopenia was a significant predictor of falling.

CONCLUSION

The key finding of the present study suggests that sarcopenia is a risk factor for falling in older adults who are living independently even after adjustment for previous falls and confounding factors. Geriatr Gerontol Int 2017; 17: 2124-2130.

摘要

目的

本研究旨在探讨老年人中是否存在肌肉减少症与未来跌倒之间的关系。

方法

本研究为为期 2 年的前瞻性观察研究。参与者从参加年度社区主办的体检且未接受护理的人群中招募。我们研究的参与者纳入标准为:(i)同意参加;(ii)独立生活;(iii)能够走到调查地点并提供自我报告数据。共有 223 名居民(82 名男性,141 名女性)参加了研究的基线评估。评估了人口统计学信息、既往跌倒史、运动机能障碍、身体功能和结构测量以及膝关节和/或腰椎疼痛。采用亚洲肌肉减少症工作组(AWGS)算法来分类是否存在肌肉减少症,并在参与者接受年度体检时评估其跌倒史。

结果

共有 162 名参与者进行了年度随访评估,其中 50 名(30.8%)在基线评估后 2 年的观察期间至少跌倒过一次。与未跌倒的参与者相比,跌倒过的参与者既往跌倒史、运动机能障碍、肌肉减少症和疼痛的发生率明显更高。多变量逻辑回归分析显示,肌肉减少症的患病率是跌倒的一个显著预测因素。

结论

本研究的主要发现表明,即使在调整了既往跌倒和混杂因素后,肌肉减少症也是独立生活的老年人跌倒的一个危险因素。老年医学与老年病学杂志 2017;17:2124-2130。

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