• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

肌少症是独立生活的日本老年人跌倒的一个风险因素:GAINA 研究的一项为期 2 年的前瞻性队列研究。

Sarcopenia is a risk factor for falling in independently living Japanese older adults: A 2-year prospective cohort study of the GAINA study.

机构信息

Rehabilitation Division, Tottori University Hospital, Yonago, Tottori, Japan.

Faculty of Medicine, School of Health Science, Tottori University, Yonago, Tottori, Japan.

出版信息

Geriatr Gerontol Int. 2017 Nov;17(11):2124-2130. doi: 10.1111/ggi.13047. Epub 2017 May 18.

DOI:10.1111/ggi.13047
PMID:28517243
Abstract

AIM

The purpose of the present study was to investigate whether sarcopenia was associated with future falls in the general Japanese older population.

METHODS

This study was a 2-year prospective observational study. Participants were recruited from individuals who had an annual town-sponsored medical check-up and had not received nursing care. The inclusion criteria for participants in our study were: (i) agreement to participate; (ii) living independently; and (iii) the ability to walk to where the survey was carried out and to provide self-reported data. A total of 223 residents (82 men, 141 women) participated in the baseline assessment in the study. Demographic information, previous fall history, locomotive syndrome, body function and structural measurements and pain at the knee and/or lumber spine were assessed. The Asian Working Group for Sarcopenia algorithm was used to classify the presence of sarcopenia, and assess the history of falling when the participant received their annual medical check-up.

RESULTS

A total of 162 participants had an annual follow-up assessment, 50 of whom (30.8%) fell at least once during the 2-year observational period after baseline assessment. Previous falling history, prevalence of locomotive syndrome, sarcopenia and pain were significantly higher in participants who had fallen compared with participants who had not. Multiple logistic regression analysis showed the prevalence of sarcopenia was a significant predictor of falling.

CONCLUSION

The key finding of the present study suggests that sarcopenia is a risk factor for falling in older adults who are living independently even after adjustment for previous falls and confounding factors. Geriatr Gerontol Int 2017; 17: 2124-2130.

摘要

目的

本研究旨在探讨老年人中是否存在肌肉减少症与未来跌倒之间的关系。

方法

本研究为为期 2 年的前瞻性观察研究。参与者从参加年度社区主办的体检且未接受护理的人群中招募。我们研究的参与者纳入标准为:(i)同意参加;(ii)独立生活;(iii)能够走到调查地点并提供自我报告数据。共有 223 名居民(82 名男性,141 名女性)参加了研究的基线评估。评估了人口统计学信息、既往跌倒史、运动机能障碍、身体功能和结构测量以及膝关节和/或腰椎疼痛。采用亚洲肌肉减少症工作组(AWGS)算法来分类是否存在肌肉减少症,并在参与者接受年度体检时评估其跌倒史。

结果

共有 162 名参与者进行了年度随访评估,其中 50 名(30.8%)在基线评估后 2 年的观察期间至少跌倒过一次。与未跌倒的参与者相比,跌倒过的参与者既往跌倒史、运动机能障碍、肌肉减少症和疼痛的发生率明显更高。多变量逻辑回归分析显示,肌肉减少症的患病率是跌倒的一个显著预测因素。

结论

本研究的主要发现表明,即使在调整了既往跌倒和混杂因素后,肌肉减少症也是独立生活的老年人跌倒的一个危险因素。老年医学与老年病学杂志 2017;17:2124-2130。

相似文献

1
Sarcopenia is a risk factor for falling in independently living Japanese older adults: A 2-year prospective cohort study of the GAINA study.肌少症是独立生活的日本老年人跌倒的一个风险因素:GAINA 研究的一项为期 2 年的前瞻性队列研究。
Geriatr Gerontol Int. 2017 Nov;17(11):2124-2130. doi: 10.1111/ggi.13047. Epub 2017 May 18.
2
FRAX score and recent fall history predict the incidence for sarcopenia in community-dwelling older adults: a prospective cohort study.FRAX 评分和近期跌倒史预测社区居住的老年人群肌少症的发生率:一项前瞻性队列研究。
Osteoporos Int. 2020 Oct;31(10):1985-1994. doi: 10.1007/s00198-020-05447-4. Epub 2020 May 24.
3
Comment on: Sarcopenia is a risk factor for falling in independently-living Japanese older adults: A 2-year prospective cohort study of the GAINA study.评论:肌肉减少症是日本独立生活的老年人跌倒的危险因素:GAINA研究的一项为期2年的前瞻性队列研究。
Geriatr Gerontol Int. 2017 Nov;17(11):2285-2286. doi: 10.1111/ggi.13123.
4
Prevalence of sarcopenia in community-dwelling Japanese older adults.社区居住的日本老年人肌少症的流行情况。
J Am Med Dir Assoc. 2013 Dec;14(12):911-5. doi: 10.1016/j.jamda.2013.08.015. Epub 2013 Oct 3.
5
The one-leg portion of the Stand-Up Test predicts fall risk in aged individuals: A prospective cohort study.起立试验的单腿部分可预测老年人的跌倒风险:一项前瞻性队列研究。
J Orthop Sci. 2020 Jul;25(4):688-692. doi: 10.1016/j.jos.2019.06.014. Epub 2019 Jul 20.
6
Sarcopenia and falls in community-dwelling elderly subjects in Japan: Defining sarcopenia according to criteria of the European Working Group on Sarcopenia in Older People.日本社区居住老年人群中的肌肉减少症与跌倒:根据老年人肌肉减少症欧洲工作组的标准定义肌肉减少症
Arch Gerontol Geriatr. 2014 Sep-Oct;59(2):295-9. doi: 10.1016/j.archger.2014.04.016. Epub 2014 May 4.
7
Sarcopenia as a risk factor for falls in elderly individuals: results from the ilSIRENTE study.肌少症作为老年人跌倒的风险因素:来自 ilSIRENTE 研究的结果。
Clin Nutr. 2012 Oct;31(5):652-8. doi: 10.1016/j.clnu.2012.02.007. Epub 2012 Mar 11.
8
[Impact of fall risk and fear of falling on mobility of independently living senior citizens transitioning to frailty: screening results concerning fall prevention in the community].[跌倒风险和跌倒恐惧对向虚弱转变的独立生活老年人活动能力的影响:社区预防跌倒的筛查结果]
Z Gerontol Geriatr. 2007 Aug;40(4):255-67. doi: 10.1007/s00391-007-0473-z.
9
Association of low back and knee pain with falls in Japanese community-dwelling older adults: A 3-year prospective cohort study.日本社区居住老年人中腰背痛和膝关节疼痛与跌倒的关联:一项为期3年的前瞻性队列研究。
Geriatr Gerontol Int. 2017 Jun;17(6):875-884. doi: 10.1111/ggi.12799. Epub 2016 May 20.
10
Falls among older adults with sarcopenia dwelling in nursing home or community: A meta-analysis.居住在养老院或社区的老年肌少症患者跌倒:一项荟萃分析。
Clin Nutr. 2020 Jan;39(1):33-39. doi: 10.1016/j.clnu.2019.01.002. Epub 2019 Jan 8.

引用本文的文献

1
Principal Component Analysis to Examine Fall-predictive Screening Tests for use during Locomotive Health Checkups.主成分分析用于检验在机车健康检查中使用的跌倒预测筛查测试。
Prog Rehabil Med. 2025 Apr 22;10:20250010. doi: 10.2490/prm.20250010. eCollection 2025.
2
Frailty in Geriatrics: A Critical Review with Content Analysis of Instruments, Overlapping Constructs, and Challenges in Diagnosis and Prognostic Precision.老年医学中的衰弱:对评估工具、重叠概念以及诊断和预后精准度挑战的批判性综述与内容分析
J Clin Med. 2025 Mar 7;14(6):1808. doi: 10.3390/jcm14061808.
3
Association between dietary variety status and sarcopenia as defined by the Asian Working Group for Sarcopenia 2019 consensus in older outpatients at a hospital specializing in geriatric medicine: A cross‑sectional study with baseline data of prospective cohort study (JUSTICE‑TOKYO study).
在一家老年医学专科医院的老年门诊患者中,根据2019年亚洲肌少症工作组共识定义的饮食多样性状况与肌少症之间的关联:一项以前瞻性队列研究(东京正义研究)基线数据为基础的横断面研究。
Biomed Rep. 2024 Jun 25;21(2):123. doi: 10.3892/br.2024.1811. eCollection 2024 Aug.
4
Physical Activity Mediates the Relationship Between Sarcopenia and Cognitive Function Among Older Adults in Nursing Homes.体力活动在养老院老年人肌少症与认知功能之间的关系中起中介作用。
Clin Interv Aging. 2023 Nov 13;18:1863-1871. doi: 10.2147/CIA.S425271. eCollection 2023.
5
Lifestyle and body composition changes in patients with rheumatoid arthritis during the COVID-19 pandemic: A retrospective, observational study.2019年冠状病毒病大流行期间类风湿关节炎患者的生活方式和身体成分变化:一项回顾性观察研究。
Osteoporos Sarcopenia. 2023 Mar;9(1):32-37. doi: 10.1016/j.afos.2023.03.003. Epub 2023 Mar 23.
6
The Relationship between Sarcopenia and Injury Events: A Systematic Review and Meta-Analysis of 98,754 Older Adults.肌肉减少症与损伤事件之间的关系:对98754名老年人的系统评价和荟萃分析
J Clin Med. 2022 Oct 31;11(21):6474. doi: 10.3390/jcm11216474.
7
Exploratory analysis using machine learning of predictive factors for falls in type 2 diabetes.使用机器学习分析 2 型糖尿病患者跌倒的预测因素的探索性分析。
Sci Rep. 2022 Jul 13;12(1):11965. doi: 10.1038/s41598-022-15224-4.
8
Sarcopenic Obesity Tendency and Nutritional Status Is Related to the Risk of Sarcopenia, Frailty, Depression and Quality of Life in Patients with Dementia.肌少症性肥胖倾向与营养状况与痴呆患者发生肌少症、衰弱、抑郁和生活质量下降的风险相关。
Int J Environ Res Public Health. 2022 Feb 22;19(5):2492. doi: 10.3390/ijerph19052492.
9
Sarcopenia May Be a Risk Factor for Osteoporosis in Chinese Patients with Rheumatoid Arthritis.肌肉减少症可能是中国类风湿关节炎患者骨质疏松症的一个危险因素。
Int J Gen Med. 2022 Feb 23;15:2075-2085. doi: 10.2147/IJGM.S349435. eCollection 2022.
10
Sex differences in impact of sarcopenia on falls in community-dwelling Korean older adults.社区居住的韩国老年人中肌少症对跌倒影响的性别差异。
BMC Geriatr. 2021 Dec 18;21(1):716. doi: 10.1186/s12877-021-02688-8.