Gaitskell Kezia
a Nuffield Department of Population Health , University of Oxford , Oxford , UK.
b The Royal Free Hospital , London , UK.
New Bioeth. 2017 Apr;23(1):21-29. doi: 10.1080/20502877.2017.1314884.
One of the promised benefits of 'personalised' medicine is that it will have a positive impact on disease screening and prevention, by enabling more person-specific estimates of risk, and hence more personalised strategies for screening and risk reduction. This article summarises some of the areas in which these approaches are already being implemented, but also outlines some of the potential difficulties and limitations - and challenges the assumption that 'personalised' approaches are necessarily superior for prevention and screening.
“个性化”医疗所带来的一项预期益处是,它将对疾病筛查和预防产生积极影响,通过实现更针对个人的风险评估,进而制定更个性化的筛查和降低风险策略。本文总结了这些方法已经在哪些领域得到应用,但也概述了一些潜在的困难、局限之处,并对“个性化”方法在预防和筛查方面必然更具优势这一假设提出了质疑。