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个性化医疗:前景、炒作与陷阱

Personalised Medicine: The Promise, the Hype and the Pitfalls.

作者信息

Feiler Therese, Gaitskell Kezia, Maughan Tim, Hordern Joshua

机构信息

a University of Oxford , UK.

出版信息

New Bioeth. 2017 Apr;23(1):1-12. doi: 10.1080/20502877.2017.1314895.

Abstract

In engaging critically with personalised medicine and mapping pitfalls which mark its progress this project aims to stimulate conversations which deal intelligently with controversies for the sake of consensus. We aim to ask the ethical questions which will lead to the improvement of healthcare and we take an open-minded approach to finding answers to them over time. What is or should be meant by 'personalised medicine' is a major theme of this issue. It is a debate bound up with question of both values in the sense of ethical reflection and value in the sense of economic return. This editorial discusses and interrelates the articles of the issue under four headings: the promise and the hype of personalised medicine; the human person and the communication of risk; data sharing and participation; value, equity and power. A key intention throughout is to provoke discourse and debate, to identify aspirations which are more grounded in myth or hype than reality and to challenge them; and to identify focussed, practical questions which need further examination.

摘要

在批判性地探讨个性化医疗并梳理其发展过程中的陷阱时,本项目旨在激发那些能明智地处理争议以达成共识的对话。我们旨在提出能推动医疗保健改善的伦理问题,并随着时间的推移以开放的心态寻求这些问题的答案。“个性化医疗”的含义是什么,或者应该是什么,是本期的一个主要主题。这是一场既与伦理反思层面的价值观问题相关,又与经济回报层面的价值问题紧密相连的辩论。本社论在四个标题下讨论并关联了本期的文章:个性化医疗的前景与炒作;人及风险沟通;数据共享与参与;价值、公平与权力。贯穿始终的一个关键意图是引发讨论和辩论,识别那些更多基于神话或炒作而非现实的愿望并对其提出质疑;以及识别需要进一步审视的重点、实际问题。

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