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PDE-5 inhibitors should be used post radical prostatectomy as erection function rehabilitation? | Opinion: No.

作者信息

Clavell-Hernández Jonathan, Wang Run

机构信息

Division of Urology, Department of Surgery, University of Texas Medical School at Houston, Houston, Texas, USA.

University of Texas, MD Anderson Cancer Center, Houston, Texas, USA.

出版信息

Int Braz J Urol. 2017 May-Jun;43(3):390-393. doi: 10.1590/S1677-5538.IBJU.2017.03.04.

DOI:10.1590/S1677-5538.IBJU.2017.03.04
PMID:28520337
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5462128/
Abstract
摘要

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Repeated Injections of Mesenchymal Stem Cell-Derived Exosomes Ameliorate Erectile Dysfunction in a Cavernous Nerve Injury Rat Model.重复注射间充质干细胞衍生的外泌体可改善海绵体神经损伤大鼠模型中的勃起功能障碍。
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本文引用的文献

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The controversy surrounding penile rehabilitation after radical prostatectomy.根治性前列腺切除术后阴茎康复的相关争议。
Transl Androl Urol. 2017 Feb;6(1):2-11. doi: 10.21037/tau.2016.08.14.
2
Effects of Tadalafil Once-Daily or On-Demand vs Placebo on Return to Baseline Erectile Function After Bilateral Nerve-Sparing Radical Prostatectomy--Results from a Randomized Controlled Trial (REACTT).他达拉非每日一次或按需服用与安慰剂对双侧保留神经的根治性前列腺切除术后勃起功能恢复至基线水平的影响——一项随机对照试验（REACTT）的结果
J Sex Med. 2016 Apr;13(4):679-83. doi: 10.1016/j.jsxm.2016.01.022. Epub 2016 Mar 25.
3
A prospective, randomized, placebo-controlled trial of on-Demand vs. nightly sildenafil citrate as assessed by Rigiscan and the international index of erectile function.一项通过阴茎硬度扫描仪（Rigiscan）和国际勃起功能指数评估按需服用与每晚服用枸橼酸西地那非的前瞻性、随机、安慰剂对照试验。
Andrology. 2016 Jan;4(1):27-32. doi: 10.1111/andr.12118. Epub 2015 Dec 10.
4
Effects of tadalafil treatment on erectile function recovery following bilateral nerve-sparing radical prostatectomy: a randomised placebo-controlled study (REACTT).他达拉非治疗双侧神经保留根治性前列腺切除术后勃起功能恢复的效果：一项随机安慰剂对照研究（REACTT）。
Eur Urol. 2014 Mar;65(3):587-96. doi: 10.1016/j.eururo.2013.09.051. Epub 2013 Oct 13.
5
Nightly vs on-demand sildenafil for penile rehabilitation after minimally invasive nerve-sparing radical prostatectomy: results of a randomized double-blind trial with placebo.微创神经保留根治性前列腺切除术后按需与每晚服用西地那非进行阴茎康复治疗的随机双盲安慰剂对照试验结果。
BJU Int. 2013 Oct;112(6):844-51. doi: 10.1111/bju.12253. Epub 2013 Aug 13.
6
Prediction of erectile function following treatment for prostate cancer.前列腺癌治疗后勃起功能的预测。
JAMA. 2011 Sep 21;306(11):1205-14. doi: 10.1001/jama.2011.1333.
7
Erectile function rehabilitation after radical prostatectomy: practice patterns among AUA members.根治性前列腺切除术后的勃起功能康复：AUA 会员的实践模式。
J Sex Med. 2011 Aug;8(8):2370-6. doi: 10.1111/j.1743-6109.2011.02355.x. Epub 2011 Jun 16.
8
Impact of age at diagnosis on prostate cancer treatment and survival.诊断时年龄对前列腺癌治疗和生存的影响。
J Clin Oncol. 2011 Jan 10;29(2):235-41. doi: 10.1200/JCO.2010.30.2075. Epub 2010 Dec 6.
9
Randomized, double-blind, placebo-controlled study of postoperative nightly sildenafil citrate for the prevention of erectile dysfunction after bilateral nerve-sparing radical prostatectomy.术后每晚服用枸橼酸西地那非预防双侧保留神经根治性前列腺切除术后勃起功能障碍的随机、双盲、安慰剂对照研究
Int J Impot Res. 2008 Sep-Oct;20(5):479-86. doi: 10.1038/ijir.2008.33. Epub 2008 Jul 24.
10
Effect of nightly versus on-demand vardenafil on recovery of erectile function in men following bilateral nerve-sparing radical prostatectomy.每晚服用伐地那非与按需服用伐地那非对双侧保留神经的根治性前列腺切除术后男性勃起功能恢复的影响。
Eur Urol. 2008 Oct;54(4):924-31. doi: 10.1016/j.eururo.2008.06.083. Epub 2008 Jul 9.