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根治性前列腺切除术后阴茎康复的相关争议。

The controversy surrounding penile rehabilitation after radical prostatectomy.

作者信息

Clavell-Hernández Jonathan, Wang Run

机构信息

Division of Urology, Department of Surgery, University of Texas Medical School at Houston, Houston, Texas, USA.

Division of Urology, Department of Surgery, University of Texas Medical School at Houston, Houston, Texas, USA;; University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

出版信息

Transl Androl Urol. 2017 Feb;6(1):2-11. doi: 10.21037/tau.2016.08.14.

DOI:10.21037/tau.2016.08.14
PMID:28217445
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5313301/
Abstract

Radical prostatectomy (RP) techniques have been refined in the last few decades. Despite nerve-sparing surgery, erectile dysfunction (ED) still seems to be affecting more than half of patients undergoing RP. Penile rehabilitation consists of understanding the mechanisms that affect erectile function (EF) and utilizing pharmacologic agents, devices or interventions to promote male sexual function before and after any insult to the penile erectile physiologic axis. There currently is a limited amount of clinical trials that assess treatments with the goal of recovering post-prostatectomy EF. The goal of this article is to assess a contemporary series of trials that study penile rehabilitation. Although the current evidence lacks to prove its irrefutable effectiveness, advancements in research and technology forecast a promising future in penile rehabilitation management.

摘要

在过去几十年中,根治性前列腺切除术(RP)技术不断完善。尽管采用了保留神经的手术,但勃起功能障碍(ED)似乎仍影响着超过一半接受RP的患者。阴茎康复包括了解影响勃起功能(EF)的机制,并在阴茎勃起生理轴受到任何损伤之前和之后,利用药物、设备或干预措施来促进男性性功能。目前评估以恢复前列腺切除术后EF为目标的治疗方法的临床试验数量有限。本文的目的是评估一系列研究阴茎康复的当代试验。尽管目前的证据不足以证明其无可争议的有效性,但研究和技术的进步预示着阴茎康复管理的前景广阔。

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A prospective, randomized, placebo-controlled trial of on-Demand vs. nightly sildenafil citrate as assessed by Rigiscan and the international index of erectile function.一项通过阴茎硬度扫描仪(Rigiscan)和国际勃起功能指数评估按需服用与每晚服用枸橼酸西地那非的前瞻性、随机、安慰剂对照试验。
Andrology. 2016 Jan;4(1):27-32. doi: 10.1111/andr.12118. Epub 2015 Dec 10.
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Urology. 2016 Feb;88:226.e1-9. doi: 10.1016/j.urology.2015.10.021. Epub 2015 Oct 29.
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