Cole Helen V, Owusu-Dabo Ellis, Iwelunmor Juliet, Newsome Valerie, Meeks Karlijn, Agyemang Charles, Jean-Louis Girardin
Center for Healthful Behavior Change, Division of Health Behavior, Department of Population Health, NYU School of Medicine, 227 E. 30th St, 6th Floor, New York, NY 10016, USA.
School of Public Health, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana; Kumasi Centre for Collaborative Research, College of Health Sciences, Kwame Nkrumah University of Science and Technology, KCCR, UPO, PMB, KNUST, Kumasi, Ghana.
Sleep Med. 2017 Jun;34:118-125. doi: 10.1016/j.sleep.2017.03.008. Epub 2017 Mar 28.
Associations between sleep duration and cardiovascular disease (CVD) risk factors have been demonstrated in past studies. However, previous studies have not investigated these relationships using objective sleep measures in sub-Saharan Africa. Our objective was to investigate the association between sleep duration and cardiovascular risk factors in a sample of community-dwelling Ghanaian adults.
We used wrist actigraphy along with a seven-day sleep diary to measure sleep duration, wake after sleep onset, sleep latency, and sleep quality. Participants were randomly selected from among those participating in the RODAM study in rural and urban Ghana. Outcome measurements included 10-year risk of CVD events, prevalent CVD, and metabolic syndrome. Additional participant characteristics were assessed using a structured questionnaire. Linear and logistic regression analyses were used to assess the relationships between sleep measures and CVD risk.
A total of 263 participants from rural and urban Ghana participated. Total sleep time was positively associated with a 10-year CVD risk; this association remained after adjusting for age, sex, urban vs rural location, socio-economic status, physical activity, and sleep disturbance (β = 0.990, p = 0.015). Short sleep, defined as sleeping less than seven hours per night on average, was negatively associated with a 10-year CVD risk, and this relationship remained in the fully adjusted model (β = -2.100, p = 0.011). Sleep duration was not associated with prevalence of CVD or metabolic syndrome.
Using actigraphy to measure sleep duration among a population of community-dwelling adults in sub-Saharan Africa is feasible. We found a positive association between sleep and CVD risk. No association was found between sleep duration and prevalent CVD or metabolic syndrome. The implications and new directions relating to these findings are stated.
过去的研究已证实睡眠时间与心血管疾病（CVD）风险因素之间存在关联。然而，以往研究尚未在撒哈拉以南非洲地区使用客观睡眠测量方法来探究这些关系。我们的目的是在一组居住在社区的加纳成年人样本中，研究睡眠时间与心血管风险因素之间的关联。
我们使用手腕活动记录仪以及为期七天的睡眠日记来测量睡眠时间、睡眠开始后觉醒时间、睡眠潜伏期和睡眠质量。参与者是从加纳农村和城市参与RODAM研究的人群中随机选取的。结局测量包括10年CVD事件风险、CVD患病率和代谢综合征。使用结构化问卷评估参与者的其他特征。采用线性和逻辑回归分析来评估睡眠测量指标与CVD风险之间的关系。
共有263名来自加纳农村和城市的参与者。总睡眠时间与10年CVD风险呈正相关；在调整年龄、性别、城乡位置、社会经济地位、身体活动和睡眠障碍后，这种关联仍然存在（β = 0.990，p = 0.015）。短睡眠定义为平均每晚睡眠少于7小时，与10年CVD风险呈负相关，并且这种关系在完全调整模型中仍然存在（β = -2.100，p = 0.011）。睡眠时间与CVD患病率或代谢综合征无关。
在撒哈拉以南非洲地区的社区居住成年人群体中，使用活动记录仪测量睡眠时间是可行的。我们发现睡眠与CVD风险之间存在正相关。未发现睡眠时间与CVD患病率或代谢综合征之间存在关联。阐述了与这些发现相关的意义和新方向。
