Monahan R C, Suttorp M M, Gabreëls B A Th F
Department of Internal Medicine, Alrijne Hospital, location Leiderdorp, the Netherlands.
Neth J Med. 2017 May;75(4):169-171.
Rivaroxaban is a direct oral anticoagulant that is prescribed for the prevention and treatment of thromboembolisms. Rivaroxaban is cleared renally and a common side effect (1-10%) is renal impairment of unknown pathophysiology. We are the first to describe a case of biopsy-proven acute tubulointerstitial nephritis, most likely caused by rivaroxaban.
利伐沙班是一种直接口服抗凝剂，用于预防和治疗血栓栓塞。利伐沙班经肾脏清除，常见副作用（1%-10%）是病因不明的肾功能损害。我们首次描述了一例经活检证实的急性肾小管间质性肾炎病例，极有可能由利伐沙班所致。
