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转移至皮肤的膀胱癌:一种预示预后不良的独特表现。

Bladder cancer that metastasized to the skin: A unique presentation that signifies poor prognosis.

作者信息

Cohen Tal, Ricchiuti Daniel, Memo Mark

机构信息

Department of Urology, Northeast Ohio Medical UniversityRootstown, OH.

N.E.O. Urology AssociatesBoardman, OH.

出版信息

Rev Urol. 2017;19(1):67-71. doi: 10.3909/riu0740.

Abstract

In the United States in 2015, an estimated 74,000 new cases of bladder cancer were diagnosed and approximately 16,000 deaths were due to bladder cancer. We present a rare case of a patient with aggressive bladder cancer who presented with multiple inguinal and scrotal skin lesions that were proven to be metastatic urothelial malignancy. Bladder malignancy can involve the skin by direct tumor invasion, hematogenous routes, lymphatic spread, and direct seeding due to iatrogenic implantation. The cutaneous lesions have an extremely variable appearance, are resistant to therapies, and signify a dismal prognosis.

摘要

2015年在美国,估计有74000例新发膀胱癌病例被诊断出来,约16000人死于膀胱癌。我们报告了一例罕见的侵袭性膀胱癌患者,该患者出现多处腹股沟和阴囊皮肤病变,经证实为转移性尿路上皮恶性肿瘤。膀胱恶性肿瘤可通过肿瘤直接侵犯、血行途径、淋巴转移以及医源性植入导致的直接播散累及皮肤。皮肤病变外观极具多样性,对治疗有抵抗性,预示着预后不良。

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