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移行细胞膀胱癌的皮肤转移:一种罕见表现及文献综述

Cutaneous metastasis of transitional cell bladder carcinoma: a rare presentation and literature review.

作者信息

Salemis Nikolaos S, Gakis Christos, Zografidis Andreas, Gourgiotis Stavros

机构信息

2nd Department of Surgery, Army General Hospital, Athens, Greece.

出版信息

J Cancer Res Ther. 2011 Apr-Jun;7(2):217-9. doi: 10.4103/0973-1482.82940.

Abstract

Cutaneous metastasis from transitional cell bladder carcinoma is a rare clinical entity associated with poor prognosis. We present a case of cutaneous metastasis arising from a transitional cell bladder carcinoma in a male patient who had undergone a radical cystectomy and bilateral ureterostomy 17 months previously. The cutaneous metastasis became evident 3 months before the manifestations of generalized recurrent disease. An awareness of this rare clinical entity and high index of suspicion is needed to rule out metastatic spread in patients with a previous history of transitional cell bladder carcinoma presenting with cutaneous nodules. Definitive diagnosis requires a histological confirmation, but prognosis is generally poor.

摘要

移行细胞膀胱癌的皮肤转移是一种罕见的临床病症,预后较差。我们报告一例男性患者,其移行细胞膀胱癌发生皮肤转移,该患者17个月前接受了根治性膀胱切除术和双侧输尿管造口术。皮肤转移在全身复发性疾病表现出现前3个月就已明显。对于有移行细胞膀胱癌病史且出现皮肤结节的患者,需要认识到这种罕见的临床病症并保持高度怀疑,以排除转移扩散。明确诊断需要组织学证实,但总体预后较差。

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