Narayana Modugumudi Ananta Satya, Patnayak Rashmi, Rukmangadha Nandyala, Chowhan Amit Kumar, Kottu Radhika, Phaneendra Bobbidi Venkatesh
Department of Pathology, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.
J Cytol. 2014 Jan;31(1):50-2. doi: 10.4103/0970-9371.130707.
Cutaneous metastasis from transitional cell carcinoma urinary bladder is a rare clinical entity associated with poor prognosis. This case report describes a 51-year-old male who presented with multiple cutaneous metastases arising from high grade transitional cell carcinoma bladder with lamina propria invasion. The prominent cytological features include medium sized to large pleomorphic cells with irregular nuclear outlines, coarse chromatin pattern, and tumor giant cells. An awareness of this rare clinical entity and high index of suspicion is needed for diagnosis.
膀胱移行细胞癌的皮肤转移是一种罕见的临床病症,预后较差。本病例报告描述了一名51岁男性,其出现了源自伴有固有层浸润的高级别膀胱移行细胞癌的多处皮肤转移。显著的细胞学特征包括中等大小至大的多形性细胞,核轮廓不规则,染色质粗糙,以及肿瘤巨细胞。诊断需要认识到这种罕见的临床病症并保持高度怀疑指数。