Suppr超能文献

视神经鞘开窗术治疗颅内压升高患者的疗效与安全性。

Efficacy and safety of optic nerve sheath fenestration in patients with raised intracranial pressure.

作者信息

Yaqub Muhammad Amer, Mehboob Mohammad Asim, Islam Qamar Ul

机构信息

Prof. Muhammad Amer Yaqub, MCPS, FCPS, FRCS. Armed Forces Institute of Ophthalmology, Rawalpindi, Pakistan.

Dr. Mohammad Asim Mehboob, MBBS. PNS Shifa Naval Hospital, Karachi, Pakistan.

出版信息

Pak J Med Sci. 2017 Mar-Apr;33(2):471-475. doi: 10.12669/pjms.332.11937.

Abstract

OBJECTIVE

To evaluate the efficacy and safety of Optic Nerve Sheath Fenestration (ONSF) in patients with raised intracranial pressure (ICP).

METHODS

This Quasi Experimental Study was conducted at Armed Forces Institute of Ophthalmology, Rawalpindi from July 2013 to July 2015. Thirty one eyes of 18 patients who underwent ONSF for raised ICP were followed up for one year to ascertain efficacy and safety of ONSF procedure.

RESULTS

Thirteen (72.22%) patients underwent ONSF bilaterally, while five (27.78%) underwent unilateral ONSF. Best corrected visual acuity (BCVA) improved in 24 (77.4%), remained stable in four (12.9%) and deteriorated in three (9.7%) patients. Papilledema improved in 27 (87.1%) while remained stable in four (12.9%) according to Frisénscale of Papilledema. Change in BCVA and papilledema from pre-operative values was statistically significant (p<0.001). There was significant negative correlation (r= -0.434, p=.017) between duration of symptoms before presentation and improvement in BCVA. Common complications were a tonic pupil, subconjunctival haemorrhage, chemosis, weakness of recti and diplopia.

CONCLUSION

ONSF is an effective procedure with statistically significant improvement in BCVA and reduction in severity of papilledema.

摘要

目的

评估视神经鞘开窗术(ONSF)治疗颅内压升高(ICP)患者的疗效和安全性。

方法

本准实验研究于2013年7月至2015年7月在拉瓦尔品第武装部队眼科研究所进行。对18例因颅内压升高接受视神经鞘开窗术的患者的31只眼睛进行了为期一年的随访,以确定视神经鞘开窗术的疗效和安全性。

结果

13例(72.22%)患者接受了双侧视神经鞘开窗术,5例(27.78%)接受了单侧视神经鞘开窗术。24例(77.4%)患者的最佳矫正视力(BCVA)有所改善,4例(12.9%)保持稳定,3例(9.7%)恶化。根据Frisén视乳头水肿分级标准,27例(87.1%)患者的视乳头水肿有所改善,4例(12.9%)保持稳定。BCVA和视乳头水肿与术前值的变化具有统计学意义(p<0.001)。症状出现前的持续时间与BCVA改善之间存在显著负相关(r = -0.434,p = 0.017)。常见并发症包括强直性瞳孔、结膜下出血、球结膜水肿、眼外肌麻痹和复视。

结论

视神经鞘开窗术是一种有效的手术,可使BCVA有统计学意义的改善,并降低视乳头水肿的严重程度。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验