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争议:视神经鞘开窗术与分流术治疗特发性颅内高压的比较

Controversies: Optic nerve sheath fenestration versus shunt placement for the treatment of idiopathic intracranial hypertension.

作者信息

Spitze Arielle, Lam Peter, Al-Zubidi Nagham, Yalamanchili Sushma, Lee Andrew G

机构信息

Department of Ophthalmology, Houston Methodist Hospital; Department of Ophthalmology, Baylor College of Medicine, Houston; Department of Ophthalmology, Neurology, and Neurosurgery, Weill Cornell Medical College, Houston; Department of Ophthalmology, The University of Iowa Hospitals and Clinics, Iowa City, IA; Department of Ophthalmology, The University of Texas Medical Branch, Galveston, TX, USA.

出版信息

Indian J Ophthalmol. 2014 Oct;62(10):1015-21. doi: 10.4103/0301-4738.146012.

Abstract

BACKGROUND

Idiopathic intracranial hypertension (IIH) has been increasing in prevalence in the past decade, following the obesity epidemic. When medical treatment fails, surgical treatment options must be considered. However, controversy remains as to which surgical procedure is the preferred surgical option - optic nerve sheath fenestration (ONSF) or cerebrospinal fluid (CSF) shunting - for the long-term treatment of this syndrome.

PURPOSE

To provide a clinical update of the pros and cons of ONSF versus shunt placement for the treatment of IIH.

DESIGN

This was a retrospective review of the current literature in the English language indexed in PubMed.

METHODS

The authors conducted a PubMed search using the following terms: Idiopathic IIH, pseudotumor cerebri, ONSF, CSF shunts, vetriculo-peritoneal shunting, and lumbo-peritoneal shunting. The authors included pertinent and significant original articles, review articles, and case reports, which revealed the new aspects and updates in these topics.

RESULTS

The treatment of IIH remains controversial and lacks randomized controlled clinical trial data. Treatment of IIH rests with the determination of the severity of IIH-related visual loss and headache.

CONCLUSION

The decision for ONSF versus shunting is somewhat institution and surgeon dependent. ONSF is preferred for patients with visual symptoms whereas shunting is reserved for patients with headache. There are positive and negative aspects of both procedures, and a prospective, randomized, controlled trial is needed (currently underway). This article will hopefully be helpful in allowing the reader to make a more informed decision until that time.

摘要

背景

在过去十年中,随着肥胖症的流行,特发性颅内高压(IIH)的患病率一直在上升。当药物治疗失败时,必须考虑手术治疗方案。然而,对于哪种手术方式是治疗该综合征的首选手术方案——视神经鞘开窗术(ONSF)还是脑脊液(CSF)分流术,仍存在争议。

目的

提供关于ONSF与分流术治疗IIH的利弊的临床最新情况。

设计

这是对PubMed索引的英文当前文献的回顾性研究。

方法

作者使用以下术语在PubMed上进行搜索:特发性IIH、假性脑瘤、ONSF、CSF分流术、脑室-腹腔分流术和腰-腹腔分流术。作者纳入了相关且重要的原创文章、综述文章和病例报告,这些文章揭示了这些主题的新方面和最新情况。

结果

IIH的治疗仍然存在争议,并且缺乏随机对照临床试验数据。IIH的治疗取决于对IIH相关视力丧失和头痛严重程度的判定。

结论

选择ONSF还是分流术在一定程度上取决于医疗机构和外科医生。有视觉症状的患者首选ONSF,而有头痛的患者则选择分流术。两种手术方式都有其优缺点,需要进行一项前瞻性、随机、对照试验(目前正在进行中)。希望本文能帮助读者在那之前做出更明智的决定。

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