Seyfried T F, Gruber M, Bitzinger D, Pawlik M T, Breu A, Graf B M, Hansen E
Department of Anesthesiology, University Hospital Regensburg, Regensburg, Germany.
Transfus Med. 2017 Aug;27(4):292-299. doi: 10.1111/tme.12421. Epub 2017 May 19.
Cell salvage plays a key role in blood conservation. To maintain high performance, quality management is recommended. Accordingly, a new-generation autotransfusion device was tested for its performance and compared with its predecessor. Two different calculations of quality parameters were applied.
In an experimental study, the continuous autotransfusion devices CATSmart and Continuous Autotransfusion System (C.A.T.S) plus were tested using banked blood adjusted to a haematocrit of 20% and anticoagulated with heparin 5 U/L. Test blood was processed using an emergency programme, a high-quality programme/smart wash programme and a low-volume wash programme. Samples were taken after the production of 200 mL of red blood cells (RBC) and after the final emptying of the separation chamber. In an additional set of tests, blood containing 1·25% fat was processed with both devices to examine fat removal.
Both devices demonstrated an equally high performance with regards to product hematocrit (Hct); RBC recovery; and elimination rates of protein, heparin and fat. The high fat elimination rate (>99·8%) reported for C.A.T.S plus was confirmed for CATSmart, regardless of the used programme. Samples taken during the ongoing process show a higher haematocrit and RBC recovery rate than samples taken after the final emptying of the separation chamber. Interface sensors were not affected by fat in the blood.
The new-generation autotransfusion device CATSmart is not inferior to its predecessor and shows high performance with regards to RBC recovery, plasma and fat elimination in all programme modes. Samples for quality controls should be taken during blood processing.
细胞回收在血液保护中起着关键作用。为保持高性能，建议进行质量管理。因此，对新一代自动输血装置进行了性能测试，并与前代产品进行了比较。应用了两种不同的质量参数计算方法。
在一项实验研究中，使用调整至血细胞比容为20%并以5 U/L肝素抗凝的库存血对连续自动输血装置CATSmart和连续自动输血系统（C.A.T.S）plus进行测试。使用紧急程序、高质量程序/智能清洗程序和低容量清洗程序处理测试血液。在产生200 mL红细胞（RBC）后以及分离腔最终排空后采集样本。在另一组测试中，用这两种装置处理含1.25%脂肪的血液以检查脂肪清除情况。
在产品血细胞比容（Hct）、RBC回收率以及蛋白质、肝素和脂肪的清除率方面，两种装置均表现出同样高的性能。无论使用何种程序，CATSmart都证实了C.A.T.S plus所报告的高脂肪清除率（>99.8%）。在处理过程中采集的样本比分离腔最终排空后采集的样本具有更高的血细胞比容和RBC回收率。接口传感器不受血液中脂肪的影响。
新一代自动输血装置CATSmart并不逊色于其前代产品，并且在所有程序模式下，在RBC回收、血浆和脂肪清除方面均表现出高性能。质量控制样本应在血液处理过程中采集。
