Origgi L, Perego R, Hu C, Bertetti E, D'Agostino P, Asero R, Riboldi P
Istituto di Medicina Interna, Università degli Studi di Milano, Italy.
Boll Ist Sieroter Milan. 1988;67(2):116-22.
Sera from 18 patients with Systemic Lupus Erythematosus (SLE), 20 with nonA-nonB acute hepatitis and 19 healthy subjects were tested for the presence of antibodies to the viral capside of Epstein-Barr virus. In patients with SLE the mean titre of anti-VCA IgG was significantly higher than in normal subjects (p less than 0.02), and the percentage of patients with titres greater than 1:160 was significantly higher than in normal population (p less than 0.01). These high anti-VCA) titres in SLE patients are probably related to a defective immune surveillance.
对18名系统性红斑狼疮(SLE)患者、20名非甲非乙型急性肝炎患者和19名健康受试者的血清进行检测,以确定是否存在针对EB病毒病毒衣壳的抗体。SLE患者中抗VCA IgG的平均滴度显著高于正常受试者(p<0.02),滴度大于1:160的患者百分比显著高于正常人群(p<0.01)。SLE患者中这些高抗VCA滴度可能与免疫监视缺陷有关。