Zymantiene J, Zelvyte R, Pampariene I, Aniuliene A, Juodziukyniene N, Kantautaite J, Oberauskas V
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Pol J Vet Sci. 2017 Mar 28;20(1):155-165. doi: 10.1515/pjvs-2017-0020.
The aim of this study was to investigate the influence of long-term building construction noise from refurbishment, which including vibration, on some physiological parameters and histopathological changes of organs of Wistar rats. Twenty 12 month old female rats were divided into two groups: rats group I (n = 10) were exposed to long-term construction noise and rats group II (n = 10) were kept under normal noise level. Study results revealed that long-term construction noise from building refurbishment has an influence on body weight, haematological and some serum biochemical parameters affects caecal microbiota, and causes histopathological changes in the organs of adult female Wistar rats. It was noticed that rats in group I exihibited significantly higher mean values for total protein, albumin and lower values for glucose, AST, ALT, blood urea nitrogen, haematological and caecal microbiota parameters than rats in group II. The most common pathologies were determined in the kidney, liver and lungs. Other observed pathologies were lymphadenopathy, catarrhal inflammation of the intestines, spleen hyperplasia and mammary gland adenofibroma. Single cases were subcutaneous fibroma in the thoracic region, abortus with uterine inflammation and thymus hyperplasia with formation of cysts were found.
本研究的目的是调查建筑翻新产生的长期施工噪声（包括振动）对Wistar大鼠某些生理参数及器官组织病理学变化的影响。将20只12月龄雌性大鼠分为两组：第一组大鼠（n = 10）暴露于长期施工噪声中，第二组大鼠（n = 10）饲养在正常噪声水平下。研究结果表明，建筑翻新产生的长期施工噪声会影响体重、血液学指标和一些血清生化参数，影响盲肠微生物群，并导致成年雌性Wistar大鼠器官出现组织病理学变化。注意到，与第二组大鼠相比，第一组大鼠的总蛋白、白蛋白平均值显著更高，而葡萄糖、谷草转氨酶、谷丙转氨酶、血尿素氮、血液学指标和盲肠微生物群参数值更低。最常见的病变发生在肾脏、肝脏和肺部。其他观察到的病变有淋巴结病、肠道卡他性炎症、脾脏增生和乳腺腺纤维瘤。发现个别病例为胸部皮下纤维瘤、伴有子宫炎症的流产以及伴有囊肿形成的胸腺增生。
