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在老年住院患者中使用添加瓜尔胶和麦麸的乳糖醇甜味酸奶治疗慢性便秘

Treatment of chronic constipation with lactitol sweetened yoghurt supplemented with guar gum and wheat bran in elderly hospital in-patients.

作者信息

Rajala S A, Salminen S J, Seppänen J H, Vapaatalo H

机构信息

Tampere City Hospital, R & D Dept., Helsinki, Finland.

出版信息

Compr Gerontol A. 1988 Jun;2(2):83-6.

PMID:2852540
Abstract

The faecal output of 33 elderly hospitalized patients was followed daily for 4 weeks. After an observation period of 1 week 18 patients received during the following 2 weeks a 150 ml portion of yoghurt containing lactitol, guar gum and wheat bran (fibre yoghurt group) twice daily. Fifteen control patients received the same volume of yoghurt without lactitol, guar gum or wheat bran (control yoghurt group). The study design was randomized double-blind. The mean faecal output increased 1.6-fold in patients receiving fibre yoghurt, while the corresponding value for control patients was 1.2 (p less than 0.05). About 50% of the fibre yoghurt group and 25% of the controls considered the treatment effective. Some in the fibre yoghurt group experienced meteorism and loose stools. No significant changes were observed in blood glucose, serum cholesterol or triglyceride values, body weights or faecal pH values in either group.

摘要

对33名老年住院患者的粪便排出量进行了为期4周的每日跟踪。在1周的观察期后,18名患者在接下来的2周内每天两次接受150毫升含有乳糖醇、瓜尔豆胶和麦麸的酸奶(纤维酸奶组)。15名对照患者接受相同体积但不含乳糖醇、瓜尔豆胶或麦麸的酸奶(对照酸奶组)。研究设计为随机双盲。接受纤维酸奶的患者平均粪便排出量增加了1.6倍,而对照患者的相应值为1.2(p<0.05)。约50%的纤维酸奶组患者和25%的对照组患者认为治疗有效。纤维酸奶组的一些患者出现了腹胀和腹泻。两组患者的血糖、血清胆固醇或甘油三酯值、体重或粪便pH值均未观察到显著变化。

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Prebiotic UG1601 mitigates constipation-related events in association with gut microbiota: A randomized placebo-controlled intervention study.
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