老年人中的益生菌和益生元。
Probiotics and prebiotics in the elderly.
作者信息
Hamilton-Miller J M T
机构信息
Department of Medical Microbiology, Royal Free and University College Medical School, Rowland Hill St, London NW3 2PF, UK.
出版信息
Postgrad Med J. 2004 Aug;80(946):447-51. doi: 10.1136/pgmj.2003.015339.
Probiotics (usually lactobacilli and bifidobacteria) and prebiotics (non-digestible oligosaccharides) have been shown to be useful in preventing certain disease conditions as well as possibly promoting specific aspects of health. In the present review, the evidence from clinical trials for benefits from probiotics and prebiotics to elderly populations is presented and discussed, specifically in respect of three common conditions found in the elderly. Both probiotics and prebiotics may be helpful in malnutrition, particularly in lactose intolerance and calcium absorption, and in constipation. Probiotics have been shown clearly to boost immunity in the elderly, but the clinical significance of this remains to be clarified. These results are encouraging, and further large scale studies seem justified to establish the place of probiotic and prebiotic supplements in elderly subjects.
益生菌（通常为乳酸菌和双歧杆菌）和益生元（不可消化的低聚糖）已被证明有助于预防某些疾病状况，并可能促进健康的特定方面。在本综述中，我们展示并讨论了来自临床试验的证据，这些证据表明益生菌和益生元对老年人群有益，特别是针对老年人中常见的三种状况。益生菌和益生元在营养不良方面可能都有帮助，尤其是在乳糖不耐受和钙吸收以及便秘方面。益生菌已被明确证明可增强老年人的免疫力，但其临床意义仍有待阐明。这些结果令人鼓舞，进一步的大规模研究似乎有必要，以确定益生菌和益生元补充剂在老年受试者中的地位。
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