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肺血管扩张剂与麻醉注意事项

Pulmonary Vasodilators and Anesthesia Considerations.

作者信息

Green Jeremy B, Hart Brendon, Cornett Elyse M, Kaye Alan D, Salehi Ali, Fox Charles J

机构信息

Department of Anesthesiology, Louisiana State University Health Science Center-New Orleans, New Orleans, LA, USA.

Department of Anesthesiology, Louisiana State University Health Science Center-Shreveport, Shreveport, LA, USA.

出版信息

Anesthesiol Clin. 2017 Jun;35(2):221-232. doi: 10.1016/j.anclin.2017.01.008. Epub 2017 Apr 14.

DOI:10.1016/j.anclin.2017.01.008
PMID:28526144
Abstract

Pulmonary hypertension (PH) is a complex disease process of the pulmonary vasculature system characterized by elevated pulmonary arterial pressures. Patients with PH are at increased risk for morbidity and mortality, including intraoperatively and postoperatively. Appreciation by the clinical anesthesiologist of the pathophysiology of PH is warranted. Careful and meticulous strategy using appropriate anesthetic medications, pulmonary vasodilator and inotropic agents, and careful fluid management all increase the likelihood of the best possible outcome in this challenging patient population.

摘要

肺动脉高压(PH)是一种以肺动脉压力升高为特征的肺血管系统复杂疾病过程。PH患者的发病和死亡风险增加,包括术中及术后。临床麻醉医生有必要了解PH的病理生理学。谨慎且细致地使用合适的麻醉药物、肺血管扩张剂和正性肌力药物,并精心进行液体管理,所有这些都增加了在这一具有挑战性的患者群体中取得最佳可能结果的可能性。

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