Wei Wei, Tang Hua-Yu, Li Yu-Zhi, Wang Tian-Shu
Second Ward of Orthopedis Department.
Department of Urology, First Affiliated Hospital of Jiamusi University, Jiamusi, China.
Medicine (Baltimore). 2019 Feb;98(7):e14511. doi: 10.1097/MD.0000000000014511.
Previous clinical trials have reported that extracorporeal shock wave (EPSW) can be used to treat low back pain (LBP), and have achieved satisfied effect. However, its effectiveness is still inconclusive. Thus, this systematic review will aim to assess the effectiveness and safety of EPSW for patients with LBP.
In this systematic review, the electronic databases of Cochrane Central Register of Controlled Trials, EMBASE, PUBMED, Cumulative Index to Nursing and Allied Health Literature, China National Knowledge Infrastructure, Chinese Biomedical Literature Database, Chinese Scientific Journal Database, and Wanfang Data will be searched from inception to January 1, 2019. Randomized controlled trials and case-control studies that assessed the effectiveness and safety of EPSW for LBP will be included. The primary outcome is pain intensity. The secondary outcomes are functional status, quality of life, psychological outcomes, as well as the adverse events. All process of the study selection, data extraction, and methodology evaluation will be carried out by two authors independently. RevMan 5.3 software will be utilized for statistical analysis.
This study will provide a detailed summary of latest evidence related to the effectiveness and safety of EPSW in pain relief, improvement of functional status, quality of life, and psychological disorders in patients with LBP.
The findings of this study may provide possible guidance for LBP treated by EPSW.
Ethical approval is not required in this study, because it will not collect the original data from individual patient. The results are expected to publish through a peer-reviewed journal.
PROSPERO CRD42019120501.
既往临床试验报道，体外冲击波（EPSW）可用于治疗腰痛（LBP），且已取得满意效果。然而，其有效性仍无定论。因此，本系统评价旨在评估EPSW治疗LBP患者的有效性和安全性。
在本系统评价中，将检索Cochrane对照试验中央注册库、EMBASE、PUBMED、护理学与健康照护领域累积索引、中国知网、中国生物医学文献数据库、中文科技期刊数据库和万方数据等电子数据库，检索时间从建库至2019年1月1日。纳入评估EPSW治疗LBP有效性和安全性的随机对照试验和病例对照研究。主要结局为疼痛强度。次要结局包括功能状态、生活质量、心理结局以及不良事件。研究选择、数据提取和方法学评估的所有过程将由两位作者独立进行。将使用RevMan 5.3软件进行统计分析。
本研究将详细总结与EPSW在缓解LBP患者疼痛、改善功能状态、生活质量和心理障碍方面的有效性和安全性相关的最新证据。
本研究结果可能为EPSW治疗LBP提供可能的指导。
本研究无需伦理批准，因为它不会从个体患者收集原始数据。研究结果有望通过同行评审期刊发表。
PROSPERO CRD42019120501
