VA Tennessee Valley Healthcare System, Nashville, Tennessee; Vanderbilt University School of Medicine, Nashville, Tennessee; W.K. Kellogg Eye Center, University of Michigan Health System, Ann Arbor, Michigan.
St. Louis VA Medical Center, St. Louis, Missouri; Washington University School of Medicine, St. Louis, Missouri.
Ophthalmology. 2017 Oct;124(10):1496-1503. doi: 10.1016/j.ophtha.2017.04.014. Epub 2017 May 16.
To compare the impact of first eye versus second eye cataract surgery on visual function and quality of life.
Cohort study.
A total of 328 patients undergoing separate first eye and second eye phacoemulsification cataract surgeries at 5 veterans affairs centers in the United States. Patients with previous ocular surgery, postoperative endophthalmitis, postoperative retinal detachment, reoperation within 30 days, dementia, anxiety disorder, hearing difficulty, or history of drug abuse were excluded.
Patients received complete preoperative and postoperative ophthalmic examinations for first eye and second eye cataract surgeries. Best-corrected visual acuity (BCVA) was measured 30 to 90 days preoperatively and postoperatively. Patients completed the National Eye Institute Visual Functioning Questionnaire (NEI-VFQ) 30 to 90 days preoperatively and postoperatively. The NEI-VFQ scores were calculated using a traditional subscale scoring algorithm and a Rasch-refined approach producing visual function and socioemotional subscale scores.
Postoperative NEI-VFQ scores and improvement in NEI-VFQ scores comparing first eye versus second eye cataract surgery.
Mean age was 70.4 years (±9.6 standard deviation [SD]). Compared with second eyes, first eyes had worse mean preoperative BCVA (0.55 vs. 0.36 logarithm of the minimum angle of resolution (logMAR), P < 0.001), greater mean BCVA improvement after surgery (-0.50 vs. -0.32 logMAR, P < 0.001), and slightly worse postoperative BCVA (0.06 vs. 0.03 logMAR, P = 0.039). Compared with first eye surgery, second eye surgery resulted in higher postoperative NEI-VFQ scores for nearly all traditional subscales (P < 0.001), visual function subscale (-3.85 vs. -2.91 logits, P < 0.001), and socioemotional subscale (-2.63 vs. -2.10 logits, P < 0.001). First eye surgery improved visual function scores more than second eye surgery (-2.99 vs. -2.67 logits, P = 0.021), but both first and second eye surgeries resulted in similar improvements in socioemotional scores (-1.62 vs. -1.51 logits, P = 0.255).
Second eye cataract surgery improves visual function and quality of life well beyond levels achieved after first eye cataract surgery alone. For certain socioemotional aspects of quality of life, second eye cataract surgery results in comparable improvement to first eye cataract surgery.
比较第一只眼和第二只眼白内障手术后对视觉功能和生活质量的影响。
队列研究。
在美国 5 个退伍军人事务中心接受单独的第一只眼和第二只眼超声乳化白内障手术的总共 328 名患者。排除了有先前眼部手术、术后眼内炎、术后视网膜脱离、术后 30 天内再次手术、痴呆、焦虑障碍、听力困难或药物滥用史的患者。
患者接受第一只眼和第二只眼白内障手术的完整术前和术后眼科检查。术前和术后 30 至 90 天测量最佳矫正视力(BCVA)。术前和术后 30 至 90 天,患者完成了国家眼科研究所视觉功能问卷(NEI-VFQ)。使用传统的子量表评分算法和产生视觉功能和社会情感子量表评分的 Rasch 改进方法计算 NEI-VFQ 分数。
术后 NEI-VFQ 评分和第一只眼与第二只眼白内障手术后 NEI-VFQ 评分的改善。
平均年龄为 70.4 岁(±9.6 标准差[SD])。与第二只眼相比,第一只眼术前平均 BCVA 更差(0.55 与 0.36 对数最小角分辨率(logMAR),P <0.001),手术后平均 BCVA 改善更大(-0.50 与-0.32 logMAR,P <0.001),术后 BCVA 略差(0.06 与 0.03 logMAR,P=0.039)。与第一只眼手术相比,第二只眼手术导致几乎所有传统子量表(P <0.001)、视觉功能子量表(-3.85 与-2.91 对数单位,P <0.001)和社会情感子量表(-2.63 与-2.10 对数单位,P <0.001)的术后 NEI-VFQ 评分更高。第一只眼手术改善的视觉功能评分高于第二只眼手术(-2.99 与-2.67 对数单位,P=0.021),但第一只眼和第二只眼手术都导致社会情感评分相似的改善(-1.62 与-1.51 对数单位,P=0.255)。
第二只眼白内障手术可显著改善第一只眼白内障手术后无法达到的视觉功能和生活质量。对于生活质量的某些社会情感方面,第二只眼白内障手术的效果与第一只眼白内障手术相当。