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一名患T淋巴细胞母细胞白血病儿童的医院获得性军团菌病和侵袭性曲霉病

Nosocomial legionellosis and invasive aspergillosis in a child with T-lymphoblastic leukemia.

作者信息

Furtwängler Rhoikos, Schlotthauer Uwe, Gärtner Barbara, Graf Norbert, Simon Arne

机构信息

Pediatric Oncology and Hematology, Children's Hospital, Saarland University and Saarland University Medical Centre, Homburg, Germany.

Institutes and State Laboratory of Medical Microbiology and Hygiene, Saarland University and Saarland University Medical Centre, Homburg, Germany.

出版信息

Int J Hyg Environ Health. 2017 Jul;220(5):900-905. doi: 10.1016/j.ijheh.2017.05.002. Epub 2017 May 13.

Abstract

Invasive aspergillosis of the lungs and the central nervous system and Legionella pneumophilia serotype 1 infection of the lungs were diagnosed in a 22-month old child during inpatient induction treatment for T-lymphoblastic leukemia. Environmental investigations i.e. samples from the hospital water system did not reveal any Legionella. The patient may have been exposed to waterborne pathogens despite terminal water filtration due to a technical device to release residual tap water from the hose after showering. A sodium chloride nose spray was found to be contaminated with the A. fumigatus isolate of the patient.

摘要

一名22个月大的儿童在接受T淋巴细胞母细胞白血病住院诱导治疗期间,被诊断出患有肺部和中枢神经系统侵袭性曲霉病以及肺部嗜肺军团菌血清型1感染。环境调查,即从医院水系统采集的样本,未发现任何军团菌。尽管有终端水过滤装置,但由于淋浴后有一个从软管释放残留自来水的技术设备,患者可能接触到了水源性病原体。发现一种氯化钠鼻喷雾剂被患者的烟曲霉分离株污染。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3467/7106519/c02f6a4f6710/gr2_lrg.jpg

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