Singh Shailja, Aich Tapas Kumar, Bhattarai Raju
Directorate General of Employment, Ministry of Labour and Employment, Government of India, New Delhi, India.
Department of Psychiatry, BRD Medical College, Gorakhpur, Uttar Pradesh, India.
Indian J Psychiatry. 2017 Jan-Mar;59(1):88-93. doi: 10.4103/0019-5545.204440.
The present study attempted to find out the relationship between positive and negative clinical symptoms and Wisconsin Card Sorting Test (WCST) performance in a group of schizophrenia patients.
Fifty schizophrenia patients were assessed using the Positive and Negative Syndrome Scale (PANSS) by a trained psychiatrist (TKA) and two groups, each of 25 positive symptom and 25 negative symptom schizophrenia patients were formed. On these fifty patients with schizophrenia and 15 normal control groups, WCST measures were applied by a clinical psychologist (SS) who remained blind to the PANSS score.
Schizophrenia diagnosis significantly affects WCST performances. One-way analysis of variance (ANOVA) revealed schizophrenia patients showed a significant impairment on all WCST indices compared with normal subjects except versus total number of correct responses. comparison (Tukey HSD Test) between means revealed that negative schizophrenia patients showed significantly worse performance on most WCST performance parameters: percent errors, perseverative responses, percent perseverative responses, perseverative errors, percent perseverative errors, and conceptual level responses.
Both positive and negative symptom schizophrenia patients have some distinct WCST measures deficits.
本研究试图找出一组精神分裂症患者的阳性和阴性临床症状与威斯康星卡片分类测验(WCST)表现之间的关系。
由一名经过培训的精神科医生(TKA)使用阳性和阴性症状量表(PANSS)对50名精神分裂症患者进行评估,并将其分为两组,每组分别有25名阳性症状精神分裂症患者和25名阴性症状精神分裂症患者。由一名对PANSS评分不知情的临床心理学家(SS)对这50名精神分裂症患者和15名正常对照组进行WCST测试。
精神分裂症诊断显著影响WCST表现。单因素方差分析(ANOVA)显示,与正常受试者相比,精神分裂症患者在所有WCST指标上均表现出显著损伤,但正确反应总数除外。均值比较(Tukey HSD检验)显示,阴性症状精神分裂症患者在大多数WCST表现参数上表现明显更差:错误百分比、持续性反应、持续性反应百分比、持续性错误、持续性错误百分比和概念水平反应。
阳性和阴性症状精神分裂症患者在WCST测试中均存在一些明显的缺陷。